Browsing Clinical Studies by author "Kilburn, Lucy"
Now showing items 21-22 of 22
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TPOAb and Thyroid Function Are Not Associated with Breast Cancer Outcome: Evidence from a Large-Scale Study Using Data from the Taxotere as Adjuvant Chemotherapy Trial (TACT, CRUK01/001).
Muller, I; Kilburn, LS; Taylor, PN; Barrett-Lee, PJ; Bliss, JM; et al. (KARGER, 2017-07-01)BACKGROUND: Small-scale studies correlated the presence of thyroid autoimmunity with both improved or worsened breast cancer outcome. OBJECTIVES: We aimed to clarify this association in a large cohort using the phase III, ... -
Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer.
Fribbens, C; Garcia Murillas, I; Beaney, M; Hrebien, S; O'Leary, B; et al. (ELSEVIER, 2017-10-04)BACKGROUND: Selection of resistance mutations may play a major role in the development of endocrine resistance. ESR1 mutations are rare in primary breast cancer but have high prevalence in patients treated with aromatase ...