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Identification of biomarkers to predict differential response to therapeutic agents in advanced triple negative breast cancer
(Institute of Cancer Research (University Of London), 2024-01-16)
Patients with triple negative breast cancer (TNBC) tend to have poor outcomes compared to other subtypes, and this is historically due to a lack of targeted therapies for these patients. PARP inhibitors have recently been ...
Molecular subtypes of cancer-associated fibroblasts and their regulation of the tumour microenvironment in pancreatic ductal adenocarcinoma.
(Institute of Cancer Research (University Of London), 2024-03-21)
Pancreatic Ductal Adenocarcinoma (PDAC) remains a leading cause of cancer-related deaths, with a 5-year survival rate of less than 10 % in Western countries. Transcriptomic analysis of PDAC in the last decade has unearthed ...