dc.contributor.author | Pericleous, S | |
dc.contributor.author | Doran, SLF | |
dc.contributor.author | Wotherspoon, A | |
dc.contributor.author | Terlizzo, M | |
dc.contributor.author | Riddell, A | |
dc.contributor.author | Brown, G | |
dc.contributor.author | Shur, J | |
dc.contributor.author | Chua, S | |
dc.contributor.author | Hujairi, N | |
dc.contributor.author | Middleton, N | |
dc.contributor.author | Cunningham, D | |
dc.contributor.author | Kumar, S | |
dc.contributor.author | Bhogal, RH | |
dc.coverage.spatial | Germany | |
dc.date.accessioned | 2022-08-23T13:43:19Z | |
dc.date.available | 2022-08-23T13:43:19Z | |
dc.date.issued | 2022-06-01 | |
dc.identifier | 16320 | |
dc.identifier.citation | World Journal of Nuclear Medicine, 2022, 21 (2), pp. 112 - 119 | |
dc.identifier.issn | 1450-1147 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/5319 | |
dc.identifier.eissn | 1607-3312 | |
dc.identifier.eissn | 1607-3312 | |
dc.identifier.doi | 10.1055/s-0042-1750332 | |
dc.description.abstract | Background Gallbladder cancer has a poor prognosis and imaging can have variable diagnostic accuracy. We assessed the ability of preoperative 18 F-fluorodeoxyglucose positron emission tomography computed tomography ( 18 F-FDG-PET/CT) imaging to predict a postoperative histological diagnosis of gallbladder cancer. Method A retrospective analysis was undertaken in a cohort of patients, who had suspected gallbladder cancer on cross-sectional imaging and that underwent preoperative FDG-PET/CT scan. The discriminatory power of FDG-PET/CT was determined in receiver operator characteristic (ROC) analysis and diagnostic accuracy parameters were estimated at different thresholds of maximum standard unit value (SUV max ) . Results Twenty-two patients were included in the study; 7 had malignant and 15 benign diagnoses. There was no statistically significant difference between the measured SUV max between the two groups ( p = 0.71). With an area under the curve of 0.486, the ROC curve did not indicate any discriminatory power of FDG-PET/CT at any potential threshold of SUV max. Conclusion This study indicates that the diagnosis of primary gallbladder cancer cannot be accurately confirmed with FDG PET/CT scanning. | |
dc.format | Electronic-eCollection | |
dc.format.extent | 112 - 119 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | THIEME MEDICAL PUBL INC | |
dc.relation.ispartof | World Journal of Nuclear Medicine | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | CT | |
dc.subject | FDG | |
dc.subject | PET | |
dc.subject | cancer | |
dc.subject | cholecystitis | |
dc.subject | diagnostic accuracy | |
dc.subject | gallbladder | |
dc.subject | thickening | |
dc.title | The Diagnostic Accuracy of 18 F-FGD-PET/CT for Cancer of the Gallbladder: A Retrospective Study. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2022-06-01 | |
dc.date.updated | 2022-08-23T13:42:05Z | |
rioxxterms.version | VoR | |
rioxxterms.versionofrecord | 10.1055/s-0042-1750332 | |
rioxxterms.licenseref.startdate | 2022-06-01 | |
rioxxterms.type | Journal Article/Review | |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/35865160 | |
pubs.issue | 2 | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Clinical Studies | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Clinical Studies/Medicine (RMH Smith Cunningham) | |
pubs.organisational-group | /ICR/Primary Group/Royal Marsden Clinical Units | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Clinical Studies/Medicine (RMH Smith Cunningham)/Medicine (RMH Smith Cunningham) (hon.) | |
pubs.publication-status | Published online | |
pubs.volume | 21 | |
icr.researchteam | Medicine (RMH) | |
dc.contributor.icrauthor | Bhogal, Ricky | |
icr.provenance | Deposited by Mr Arek Surman on 2022-08-23. Deposit type is initial. No. of files: 1. Files: The Diagnostic Accuracy of sup18sup F-FGD-PETCT for Cancer of the Gallbladder A Retrospective Study.pdf | |