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Patient-derived organoids model treatment response of metastatic gastrointestinal cancers. 

Vlachogiannis, G; Hedayat, S; Vatsiou, A; Jamin, Y; Fernández-Mateos, J; et al. (2018-02)
Patient-derived organoids (PDOs) have recently emerged as robust preclinical models; however, their potential to predict clinical outcomes in patients has remained unclear. We report on a living biobank of PDOs from ...
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MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma. 

Lampis, A; Carotenuto, P; Vlachogiannis, G; Cascione, L; Hedayat, S; et al. (2018-03)
BACKGROUND & AIMS:Cholangiocarcinomas (CCA) are resistant to chemotherapy, so new therapeutic agents are needed. We performed a screen to identify small-molecule compounds that are active against CCAs. Levels of microRNA ...

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Author
Braconi, Chiara (2)
Burke, Rosemary (2)Clarke, Paul (2)
Cunningham, David (2)
Hahne, Jens (2)... View MoreSubjectAnimals (2)Antineoplastic Agents (2)
Drug Resistance, Neoplasm (2)
Humans (2)Organoids (2)... View MoreDate Issued
2018 (2)
Publication TypeJournal Article (2)
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