Browsing by author "Tape, Christopher"
Now showing items 1-6 of 6
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Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion.
(2019-11)Lymph nodes (LNs) act as filters, constantly sampling peripheral cues. This is facilitated by the conduit network, a tubular structure of aligned extracellular matrix (ECM) fibrils ensheathed by fibroblastic reticular cells ... -
The Heterocellular Emergence of Colorectal Cancer.
(2017-02)Tissues contain multiple different cell types and can be considered to be heterocellular systems. Signaling between different cells allows tissues to achieve phenotypes that no cell type can achieve in isolation. Such ... -
Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis.
(2016-02-16)<h4>Background</h4>The intra-tumor diversity of cancer cells is under intense investigation; however, little is known about the heterogeneity of the tumor microenvironment that is key to cancer progression and evolution. ... -
Proteomics profiling of interactome dynamics by colocalisation analysis (COLA).
(2016-12)Localisation and protein function are intimately linked in eukaryotes, as proteins are localised to specific compartments where they come into proximity of other functionally relevant proteins. Significant co-localisation ... -
Reproducible automated phosphopeptide enrichment using magnetic TiO2 and Ti-IMAC.
(2014-10-02)Reproducible, comprehensive phosphopeptide enrichment is essential for studying phosphorylation-regulated processes. Here, we describe the application of hyper-porous magnetic TiO2 and Ti-IMAC microspheres for uniform ...
