Browsing ICR Divisions by author "Tomita, Naoko"
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Neuregulin-3 regulates epithelial progenitor cell positioning and specifies mammary phenotype.
Kogata, N; Oliemuller, E; Wansbury, O; Howard, BA (MARY ANN LIEBERT, INC, 2014-11-15)Mutation of Neuregulin-3 (Nrg3) results in defective embryonic mammary gland development. Here, we investigate functions of Nrg3 signaling in embryonic mammary morphogenesis. Nrg3 regulates the distribution of epithelial ... -
SOX11 promotes invasive growth and ductal carcinoma in situ progression.
Oliemuller, E; Kogata, N; Bland, P; Kriplani, D; Daley, F; et al. (WILEY, 2017-10-01)Here, we show that SOX11, an embryonic mammary marker that is normally silent in postnatal breast cells, is expressed in many oestrogen receptor-negative preinvasive ductal carcinoma in situ (DCIS) lesions. Mature mammary ...