Browsing ICR Divisions by author "Johnston"
Now showing items 1-13 of 13
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Developing and testing a robotic MRI/CT fusion biopsy technique using a purpose-built interventional phantom.
Johnston, EW; Fotiadis, N; Cummings, C; Basso, J; Tyne, T; et al. (SPRINGER WIEN, 2022-11-22)BACKGROUND: Magnetic resonance imaging (MRI) can be used to target tumour components in biopsy procedures, while the ability to precisely correlate histology and MRI signal is crucial for imaging biomarker validation. ... -
Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial.
Taylor, SA; Mallett, S; Beare, S; Bhatnagar, G; Blunt, D; et al. (ELSEVIER INC, 2019-07-01)BACKGROUND: Whole-body MRI (WB-MRI) could be an alternative to multimodality staging of colorectal cancer, but its diagnostic accuracy, effect on staging times, number of tests needed, cost, and effect on treatment decisions ... -
Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed non-small-cell lung cancer: the prospective Streamline L trial.
Taylor, SA; Mallett, S; Ball, S; Beare, S; Bhatnagar, G; et al. (ELSEVIER SCI LTD, 2019-06-01)BACKGROUND: Whole-body magnetic resonance imaging (WB-MRI) could be an alternative to multi-modality staging of non-small-cell lung cancer (NSCLC), but its diagnostic accuracy, effect on staging times, number of tests ... -
Frequency and risk factors for major complications after stereotactic radiofrequency ablation of liver tumors in 1235 ablation sessions: a 15-year experience.
Schullian, P; Johnston, E; Laimer, G; Putzer, D; Eberle, G; et al. (SPRINGER, 2021-05-01)OBJECTIVES: To assess the frequency of major complications after multi-probe stereotactic radiofrequency ablation (SRFA) in a large cohort of patients over 15 years and to elucidate risk factors for adverse events. MATERIALS ... -
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; et al. (ELSEVIER, 2017-10-01)BACKGROUND: Intratumoural heterogeneity (ITH) is well recognised in prostate cancer (PC), but its role in high-risk disease is uncertain. A prospective, single-arm, translational study using targeted multiregion prostate ... -
National implementation of multi-parametric magnetic resonance imaging for prostate cancer detection - recommendations from a UK consensus meeting.
Brizmohun Appayya, M; Adshead, J; Ahmed, HU; Allen, C; Bainbridge, A; et al. (WILEY, 2018-07-01)OBJECTIVES: To identify areas of agreement and disagreement in the implementation of multi-parametric magnetic resonance imaging (mpMRI) of the prostate in the diagnostic pathway. MATERIALS AND METHODS: Fifteen UK experts ... -
Relationship between IHC4 score and response to neo-adjuvant chemotherapy in estrogen receptor-positive breast cancer.
Sheri, A; Smith, IE; Hills, M; Jones, RL; Johnston, SR; et al. (2017-07)Aims To determine whether IHC4 score assessed on pre-treatment core biopsies (i) predicts response to neo-adjuvant chemotherapy in ER-positive (ER+) breast cancer; (ii) provides more predictive information than Ki67 ... -
Reliability of Stereotactic Radiofrequency Ablation (SRFA) for Malignant Liver Tumors: Novice versus Experienced Operators.
Schullian, P; Laimer, G; Johnston, E; Putzer, D; Eberle, G; et al. (MDPI, 2023-01-22)PURPOSE: To compare the results of a novice with those of experienced interventional radiologists (IRs) for stereotactic radiofrequency ablation (SRFA) of malignant liver tumors in terms of safety, technical success, and ... -
Robotic versus freehand CT-guided radiofrequency ablation of pulmonary metastases: a comparative cohort study.
Johnston, EW; Basso, J; Silva, F; Haris, A; Jones, RL; et al. (SPRINGER HEIDELBERG, 2023-04-18)PURPOSE: Radiofrequency ablation (RFA) is a curative treatment option for small lung metastases, which conventionally involves multiple freehand manipulations until the treating electrode is satisfactorily positioned. ... -
Starting CT-guided robotic interventional oncology at a UK centre.
Johnston, EW; Basso, J; Winfield, J; McCall, J; Khan, N; et al. (BRITISH INST RADIOLOGY, 2022-06-01)OBJECTIVE: A commercially available CT-guided robot offers enhanced abilities in planning, targeting, and confirming accurate needle placement. In this short communication, we describe our first UK experience of robotic ... -
Stereotactic Radiofrequency Ablation of Breast Cancer Liver Metastases: Short- and Long-Term Results with Predicting Factors for Survival.
Schullian, P; Johnston, E; Laimer, G; Putzer, D; Eberle, G; et al. (SPRINGER, 2021-08-01)PURPOSE: To evaluate safety, local oncological control, long-term outcome and potential prognostic factors of stereotactic RFA (SRFA) for the treatment of BCLMs. METHODS: Between July 2003 and December 2019, 42 consecutive ... -
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth.
Scott, E; Hodgson, K; Calle, B; Turner, H; Cheung, K; et al. (SPRINGERNATURE, 2023-03-16)Prostate cancer is the most common cancer in men and it is estimated that over 350,000 men worldwide die of prostate cancer every year. There remains an unmet clinical need to improve how clinically significant prostate ... -
Virtual Biopsy in Soft Tissue Sarcoma. How Close Are We?
Arthur, A; Johnston, EW; Winfield, JM; Blackledge, MD; Jones, RL; et al. (FRONTIERS MEDIA SA, 2022-07-01)A shift in radiology to a data-driven specialty has been unlocked by synergistic developments in imaging biomarkers (IB) and computational science. This is advancing the capability to deliver "virtual biopsies" within ...