Browsing ICR Divisions by author "Cooper, Alexandra"
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An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions.
Radzisheuskaya, A; Peña-Rømer, I; Lorenzini, E; Koche, R; Zhan, Y; et al. (WILEY, 2023-12-11)Efficient treatment of acute myeloid leukemia (AML) patients remains a challenge despite recent therapeutic advances. Here, using a CRISPRi screen targeting chromatin factors, we identified the nucleosome-remodeling factor ...