Browsing ICR Divisions by author "Melake, Johanna Miriam"
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Generation and characterisation of two D2A1 mammary cancer sublines to model spontaneous and experimental metastasis in a syngeneic BALB/c host.
Jungwirth, U; van Weverwijk, A; Melake, MJ; Chambers, AF; Gao, Q; et al. (COMPANY BIOLOGISTS LTD, 2018-01-18)Studying the complex mechanisms underlying breast cancer metastasis and therapy response necessitates relevant in vivo models, particularly syngeneic models with an intact immune system. Two syngeneic spontaneously metastatic ... -
OX40 and 4-1BB delineate distinct immune profiles in sarcoma.
Melake, MJ; Smith, HG; Mansfield, D; Davies, E; Dillon, MT; et al. (TAYLOR & FRANCIS INC, 2022-12-31)Systemic relapse after radiotherapy and surgery is the major cause of disease-related mortality in sarcoma patients. Combining radiotherapy and immunotherapy is under investigation as a means to improve response rates. ...