Browsing ICR Divisions by author "Macklin-Doherty, Aislinn"
Now showing items 1-5 of 5
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Accountability in the NHS: the impact on cancer care.
Macklin-Doherty, A (Ecancer Global Foundation, 2018-01-01)Accountability of service delivery is becoming increasingly complex and never has this been more apparent than in the field of Oncology. Cancer care has an unrivalled level of complexity not only in the heterogeneity of ... -
Impact of pharmacogenomic DPYD variant guided dosing on toxicity in patients receiving fluoropyrimidines for gastrointestinal cancers in a high-volume tertiary centre.
Lau, DK; Fong, C; Arouri, F; Cortez, L; Katifi, H; et al. (BMC, 2023-04-26)BACKGROUND: Dihydropyrimidine dehydrogenase (DPD) is a key enzyme in the metabolism of fluoropyrimidines. Variations in the encoding DPYD gene are associated with severe fluoropyrimidine toxicity and up-front dose reductions ... -
Investigating a range of late effects of Hodgkin lymphoma treatments
Swerdlow, A; Macklin-Doherty, A (Institute of Cancer Research (University Of London), 2021-01-31)Dramatic improvement in Hodgkin lymphoma (HL) survival rates over recent decades has come at significant cost: treatment-related late effects which are epitomised in female HL patients treated at young ages. The aims of ... -
Risk of thyroid disorders in adult and childhood Hodgkin lymphoma survivors 40 years after treatment.
Macklin-Doherty, A; Jones, M; Coulson, P; Bruce, C; Chau, I; et al. (TAYLOR & FRANCIS LTD, 2022-02-23)Thyroid abnormalities are well reported following childhood treatment for Hodgkin Lymphoma (HL). Limited information exists for adult patients and after modern treatments. We analyzed risks of thyroid disorders in 237 ... -
Telemedicine During the COVID-19 Pandemic: Impact on Care for Rare Cancers.
Smrke, A; Younger, E; Wilson, R; Husson, O; Farag, S; et al. (AMER SOC CLINICAL ONCOLOGY, 2020-06-01)PURPOSE: Many patients with cancer, often those with rare cancers such as sarcomas, travel long distances to access expert care. The COVID-19 pandemic necessitated widespread changes in delivery of cancer care, including ...