Browsing ICR Divisions by author "Tripp, Aurelien"
Now showing items 1-3 of 3
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Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric H3.3-Mutated Gliomas Recreate the Patient Tumor Complexity.
Blandin, A-F; Durand, A; Litzler, M; Tripp, A; Guérin, É; et al. (MDPI, 2019-11-26)BACKGROUND: Pediatric high-grade gliomas (pHGGs) are facing a very dismal prognosis and representative pre-clinical models are needed for new treatment strategies. Here, we examined the relevance of collecting functional, ... -
Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids.
Koundouros, N; Karali, E; Tripp, A; Valle, A; Inglese, P; et al. (CELL PRESS, 2020-06-25)Oncogenic transformation is associated with profound changes in cellular metabolism, but whether tracking these can improve disease stratification or influence therapy decision-making is largely unknown. Using the iKnife ... -
Metabolic phenotyping using the iKnife identifies IRS2 as a driver of lipid metabolism reprogramming in colorectal cancer
Poulogiannis G; Tripp, A; Poulogiannis, G (Institute of Cancer Research (University Of London), 2022-11-22)The advent of precision medicine is changing the clinicians' approach to therapeutic decisions. It also implies that the identification of biomarkers and discriminating factors is necessary for more effective treatment ...