Browsing ICR Divisions by author "Richards, Gareth"
Now showing items 1-3 of 3
-
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen.
Cheeseman, MD; Chessum, NEA; Rye, CS; Pasqua, AE; Tucker, MJ; et al. (AMER CHEMICAL SOC, 2017-01-12)Phenotypic screens, which focus on measuring and quantifying discrete cellular changes rather than affinity for individual recombinant proteins, have recently attracted renewed interest as an efficient strategy for drug ... -
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3‑nitrobenzanthrone
Mirza, A; Arlt, VM; Meinl, W; Florian, S; Nagy, E; et al. -
Synthesis and Evaluation of a 2,11-Cembranoid-Inspired Library.
Welford, AJ; Caldwell, JJ; Liu, M; Richards, M; Brown, N; et al. (WILEY-V C H VERLAG GMBH, 2016-04-11)The 2,11-cembranoid family of natural products has been used as inspiration for the synthesis of a structurally simplified, functionally diverse library of octahydroisobenzofuran-based compounds designed to augment a typical ...