Browsing ICR Divisions by author "Collins, David"
Now showing items 1-20 of 39
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A generalized framework unifying image registration and respiratory motion models and incorporating image reconstruction, for partial image data or full images.
McClelland, JR; Modat, M; Arridge, S; Grimes, H; D'Souza, D; et al. (IOP PUBLISHING LTD, 2017-06-07)Surrogate-driven respiratory motion models relate the motion of the internal anatomy to easily acquired respiratory surrogate signals, such as the motion of the skin surface. They are usually built by first using image ... -
Accelerating Whole-Body Diffusion-weighted MRI with Deep Learning-based Denoising Image Filters.
Zormpas-Petridis, K; Tunariu, N; Curcean, A; Messiou, C; Curcean, S; et al. (RADIOLOGICAL SOC NORTH AMERICA (RSNA), 2021-09-01)PURPOSE: To use deep learning to improve the image quality of subsampled images (number of acquisitions = 1 [NOA1]) to reduce whole-body diffusion-weighted MRI (WBDWI) acquisition times. MATERIALS AND METHODS: Both ... -
Assessment of treatment response by total tumor volume and global apparent diffusion coefficient using diffusion-weighted MRI in patients with metastatic bone disease: a feasibility study.
Blackledge, MD; Collins, DJ; Tunariu, N; Orton, MR; Padhani, AR; et al. (PUBLIC LIBRARY SCIENCE, 2014-04-07)We describe our semi-automatic segmentation of whole-body diffusion-weighted MRI (WBDWI) using a Markov random field (MRF) model to derive tumor total diffusion volume (tDV) and associated global apparent diffusion coefficient ... -
Characterisation of fibrosis in chemically-induced rat mammary carcinomas using multi-modal endogenous contrast MRI on a 1.5T clinical platform.
Jerome, NP; Boult, JKR; Orton, MR; d'Arcy, JA; Nerurkar, A; et al. (SPRINGER, 2018-04-01)OBJECTIVES: To determine the ability of multi-parametric, endogenous contrast MRI to detect and quantify fibrosis in a chemically-induced rat model of mammary carcinoma. METHODS: Female Sprague-Dawley rats (n=18) were ... -
DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases.
Rata, M; Khan, K; Collins, DJ; Koh, D-M; Tunariu, N; et al. (BMC, 2021-12-19)BACKGROUND: Diffusion weighted imaging (DWI) with intravoxel incoherent motion (IVIM) modelling can inform on tissue perfusion without exogenous contrast administration. Dynamic-contrast-enhanced (DCE) MRI can also ... -
Development of a temperature-controlled phantom for magnetic resonance quality assurance of diffusion, dynamic, and relaxometry measurements.
Jerome, NP; Papoutsaki, M-V; Orton, MR; Parkes, HG; Winfield, JM; et al. (WILEY, 2016-06-01)PURPOSE: Diffusion-weighted (DW) and dynamic contrast-enhanced magnetic resonance imaging (MRI) are increasingly applied for the assessment of functional tissue biomarkers for diagnosis, lesion characterization, or for ... -
Diffusion-weighted Imaging as a Treatment Response Biomarker for Evaluating Bone Metastases in Prostate Cancer: A Pilot Study.
Perez-Lopez, R; Mateo, J; Mossop, H; Blackledge, MD; Collins, DJ; et al. (RADIOLOGICAL SOC NORTH AMERICA, 2017-04-01)Purpose To determine the usefulness of whole-body diffusion-weighted imaging (DWI) to assess the response of bone metastases to treatment in patients with metastatic castration-resistant prostate cancer (mCRPC). Materials ... -
Distortion correction of echo-planar diffusion-weighted images of uterine cervix.
deSouza, NM; Orton, M; Downey, K; Morgan, VA; Collins, DJ; et al. (WILEY-BLACKWELL, 2016-05-01)PURPOSE: To investigate the clinical utility of the reverse gradient algorithm in correcting distortions in diffusion-weighted images of the cervix and for increasing diagnostic performance. MATERIALS AND METHODS: Forty-one ... -
Early Response to Chemotherapy in Malignant Pleural Mesothelioma Evaluated Using Diffusion-Weighted Magnetic Resonance Imaging: Initial Observations.
Curcean, S; Cheng, L; Picchia, S; Tunariu, N; Collins, D; et al. (ELSEVIER, 2021-12-01)INTRODUCTION: We compared the magnetic resonance imaging total tumor volume (TTV) and median apparent diffusion coefficient (ADC) of malignant pleural mesothelioma (MPM) before and at 4 weeks after chemotherapy, to evaluate ... -
Emerging strategies for the treatment of advanced small cell lung cancer.
Lim, JSJ; Collins, D; Yap, TA (AME PUBLISHING COMPANY, 2016-10-01) -
Extended T2-IVIM model for correction of TE dependence of pseudo-diffusion volume fraction in clinical diffusion-weighted magnetic resonance imaging.
Jerome, NP; d'Arcy, JA; Feiweier, T; Koh, D-M; Leach, MO; et al. (IOP PUBLISHING LTD, 2016-12-21)The bi-exponential intravoxel-incoherent-motion (IVIM) model for diffusion-weighted MRI (DWI) fails to account for differential T 2 s in the model compartments, resulting in overestimation of pseudodiffusion fraction f. ... -
Extracranial Soft-Tissue Tumors: Repeatability of Apparent Diffusion Coefficient Estimates from Diffusion-weighted MR Imaging.
Winfield, JM; Tunariu, N; Rata, M; Miyazaki, K; Jerome, NP; et al. (RADIOLOGICAL SOC NORTH AMERICA, 2017-07-01)Purpose To assess the repeatability of apparent diffusion coefficient (ADC) estimates in extracranial soft-tissue diffusion-weighted magnetic resonance imaging across a wide range of imaging protocols and patient populations. ... -
Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study.
Khan, K; Rata, M; Cunningham, D; Koh, D-M; Tunariu, N; et al. (BMJ PUBLISHING GROUP, 2018-08-01)OBJECTIVE: Regorafenib demonstrated efficacy in patients with metastatic colorectal cancer (mCRC). Lack of predictive biomarkers, potential toxicities and cost-effectiveness concerns highlight the unmet need for better ... -
Guidelines for Acquisition, Interpretation, and Reporting of Whole-Body MRI in Myeloma: Myeloma Response Assessment and Diagnosis System (MY-RADS).
Messiou, C; Hillengass, J; Delorme, S; Lecouvet, FE; Moulopoulos, LA; et al. (RADIOLOGICAL SOC NORTH AMERICA, 2019-04-01)Acknowledging the increasingly important role of whole-body MRI for directing patient care in myeloma, a multidisciplinary, international, and expert panel of radiologists, medical physicists, and hematologists with specific ... -
Implementing diffusion-weighted MRI for body imaging in prospective multicentre trials: current considerations and future perspectives.
deSouza, NM; Winfield, JM; Waterton, JC; Weller, A; Papoutsaki, M-V; et al. (SPRINGER, 2018-03-01)UNLABELLED: For body imaging, diffusion-weighted MRI may be used for tumour detection, staging, prognostic information, assessing response and follow-up. Disease detection and staging involve qualitative, subjective ... -
Inter- and Intra-Observer Repeatability of Quantitative Whole-Body, Diffusion-Weighted Imaging (WBDWI) in Metastatic Bone Disease.
Blackledge, MD; Tunariu, N; Orton, MR; Padhani, AR; Collins, DJ; et al. (PUBLIC LIBRARY SCIENCE, 2016-04-28)Quantitative whole-body diffusion-weighted MRI (WB-DWI) is now possible using semi-automatic segmentation techniques. The method enables whole-body estimates of global Apparent Diffusion Coefficient (gADC) and total Diffusion ... -
Lung volume reproducibility under ABC control and self-sustained breath-holding.
Kaza, E; Dunlop, A; Panek, R; Collins, DJ; Orton, M; et al. (WILEY, 2017-03-01)An Active Breathing Coordinator (ABC) can be employed to induce breath-holds during CT imaging and radiotherapy of lung, breast and liver cancer, and recently during lung cancer MRI. The apparatus measures and controls ... -
METastasis Reporting and Data System for Prostate Cancer: Practical Guidelines for Acquisition, Interpretation, and Reporting of Whole-body Magnetic Resonance Imaging-based Evaluations of Multiorgan Involvement in Advanced Prostate Cancer.
Padhani, AR; Lecouvet, FE; Tunariu, N; Koh, D-M; De Keyzer, F; et al. (ELSEVIER SCIENCE BV, 2017-01-01)CONTEXT: Comparative reviews of whole-body magnetic resonance imaging (WB-MRI) and positron emission tomography/computed tomography (CT; with different radiotracers) have shown that metastasis detection in advanced cancers ... -
Microstructure Characterization of Bone Metastases from Prostate Cancer with Diffusion MRI: Preliminary Findings.
Bailey, C; Collins, DJ; Tunariu, N; Orton, MR; Morgan, VA; et al. (FRONTIERS MEDIA SA, 2018-02-16)PURPOSE: To examine the usefulness of rich diffusion protocols with high b-values and varying diffusion time for probing microstructure in bone metastases. Analysis techniques including biophysical and mathematical models ... -
Modulation of renal oxygenation and perfusion in rat kidney monitored by quantitative diffusion and blood oxygen level dependent magnetic resonance imaging on a clinical 1.5T platform.
Jerome, NP; Boult, JKR; Orton, MR; d'Arcy, J; Collins, DJ; et al. (BIOMED CENTRAL LTD, 2016-10-03)BACKGROUND: To investigate the combined use of intravoxel incoherent motion (IVIM) diffusion-weighted (DW) and blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) to assess rat renal function using a 1.5T ...