Browsing ICR Divisions by author "So, Chi Wai Eric"

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    • Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential 

      Wong, P; Iwasaki, M; Somervaille, TCP; So, CWE; Cleary, ML (COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 2007-11-01)
      Oncogenic mutations of the MLL histone methyltransferase confer an unusual ability to transform non-self-renewing myeloid progenitors into leukemia stem cells (LSCs) by mechanisms that remain poorly defined. Misregulation ...