Browsing ICR Divisions by author "Linding, Rune"
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DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization
Reinhardt, HC; Hasskamp, P; Schmedding, I; Morandell, S; van Vugt, MATM; et al. (CELL PRESS, 2010-10-08)Following genotoxic stress, cells activate a complex kinase-based signaling network to arrest the cell cycle and initiate DNA repair. p53-defective tumor cells rewire their checkpoint response and become dependent on the ...