Browsing ICR Divisions by author "Martin, Peter"
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The Biochemical Role of the Human NEIL1 and NEIL3 DNA Glycosylases on Model DNA Replication Forks
Albelazi,; Martin,; Mohammed,; Mutti,; Elder, (MDPI AG, 2019-04-23)<jats:p>Endonuclease VIII-like (NEIL) 1 and 3 proteins eliminate oxidative DNA base damage and psoralen DNA interstrand crosslinks through initiation of base excision repair. Current evidence points to a DNA replication ... -
The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure
Martin, PR; Couvé, S; Zutterling, C; Albelazi, MS; Groisman, R; et al. (Springer Science and Business Media LLC, 2017-12-01)<jats:title>Abstract</jats:title><jats:p>Interstrand cross-links (ICLs) are highly cytotoxic DNA lesions that block DNA replication and transcription by preventing strand separation. Previously, we demonstrated that the ...