Browsing ICR Divisions by author "Douglas, Maxwell"
Now showing items 1-3 of 3
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Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitro.
Douglas, ME; Diffley, JFX (OXFORD UNIV PRESS, 2021-06-04)Telomeres are copied and reassembled each cell division cycle through a multistep process called telomere replication. Most telomeric DNA is duplicated semiconservatively during this process, but replication forks frequently ... -
DNA-PK controls Apollo's access to leading-end telomeres.
Sonmez, C; Toia, B; Eickhoff, P; Matei, AM; El Beyrouthy, M; et al. (OXFORD UNIV PRESS, 2024-05-08)The complex formed by Ku70/80 and DNA-PKcs (DNA-PK) promotes the synapsis and the joining of double strand breaks (DSBs) during canonical non-homologous end joining (c-NHEJ). In c-NHEJ during V(D)J recombination, DNA-PK ... -
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis.
Capalbo, L; Bassi, ZI; Geymonat, M; Todesca, S; Copoiu, L; et al. (NATURE PUBLISHING GROUP, 2019-10-04)The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at the end of mitosis. It controls the final separation of the daughter cells and has been involved in cell fate, polarity, ...