Browsing ICR Divisions by author "Orton, Matthew"

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Characterisation of fibrosis in chemically-induced rat mammary carcinomas using multi-modal endogenous contrast MRI on a 1.5T clinical platform.

Jerome, NP; Boult, JKR; Orton, MR; d'Arcy, JA; Nerurkar, A; et al. (SPRINGER, 2018-04-01)

OBJECTIVES: To determine the ability of multi-parametric, endogenous contrast MRI to detect and quantify fibrosis in a chemically-induced rat model of mammary carcinoma. METHODS: Female Sprague-Dawley rats (n=18) were ...
Modeling non‐linear kinetics of hyperpolarized [1‐<sup>13</sup>C] pyruvate in the crystalloid‐perfused rat heart

Mariotti, E; Orton, MR; Eerbeek, O; Ashruf, JF; Zuurbier, CJ; et al. (Wiley, 2016-04-01)

<jats:p>Hyperpolarized <jats:sup>13</jats:sup>C MR measurements have the potential to display non‐linear kinetics. We have developed an approach to describe possible non‐first‐order kinetics of hyperpolarized [1‐<jats:su ...

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