Browsing ICR Divisions by author "Tari, Haider"
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Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking.
Cresswell, GD; Nichol, D; Spiteri, I; Tari, H; Zapata, L; et al. (NATURE PORTFOLIO, 2020-03-27)Circulating tumour DNA (ctDNA) allows tracking of the evolution of human cancers at high resolution, overcoming many limitations of tissue biopsies. However, exploiting ctDNA to determine how a patient's cancer is evolving ... -
Mathematical modelling of subclonal interactions in paediatric high-grade gliomas
Tari, H (Institute of Cancer Research (University Of London), 2022-05-31)Despite a low overall mutational burden, paediatric high-grade gliomas (pHGG) display high intra-tumour heterogeneity. Accumulating evidence suggest the presence of cellular mechanisms that maintain such high heterogeneity, ...