Browsing ICR Divisions by author "Bamber, Jeffrey"
Now showing items 21-40 of 55
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Further characterization of changes in axial strain elastograms due to the presence of slippery tumor boundaries.
Uff, C; Garcia, L; Fromageau, J; Chakraborty, A; Dorward, N; et al. (SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS, 2018-04-01)Elastography measures tissue strain, which can be interpreted under certain simplifying assumptions to be representative of the underlying stiffness distribution. This is useful in cancer diagnosis where tumors tend to ... -
Gold nanorod reshaping in vitro and in vivo using a continuous wave laser.
Harris-Birtill, D; Singh, M; Zhou, Y; Shah, A; Ruenraroengsak, P; et al. (PUBLIC LIBRARY SCIENCE, 2017-10-18)Gold nanorods (GNRs) are increasingly being investigated for cancer theranostics as they possess features which lend themselves in equal measures as contrast agents and catalysts for photothermal therapy. Their optical ... -
High frequency ultrasound vibrational shear wave elastography for preclinical research.
Civale, J; Parasaram, V; Bamber, JC; Harris, EJ (IOP Publishing Ltd, 2022-12-07)Preclinical evaluation of novel therapies using models of cancer is an important tool in cancer research, where imaging can provide non-invasive tools to characterise the internal structure and function of tumours. The ... -
High-contrast 3D in vivo microvascular imaging using scanning 2D ultrasound and acoutic sub-aperture processing (ASAP)
Leow, CH; Bush, NL; Stanziola, A; Braga, M; Shah, A; et al. (IEEE, 2018-01-01) -
High-frequency ultrasound for diagnosing skin cancer in adults.
Dinnes, J; Bamber, J; Chuchu, N; Bayliss, SE; Takwoingi, Y; et al. (WILEY, 2018-12-04)BACKGROUND: Early, accurate detection of all skin cancer types is essential to guide appropriate management and to improve morbidity and survival. Melanoma and squamous cell carcinoma (SCC) are high-risk skin cancers with ... -
Improving 3D ultrasound prostate localisation in radiotherapy through increased automation of interfraction matching.
Grimwood, A; Rivaz, H; Zhou, H; McNair, HA; Jakubowski, K; et al. (ELSEVIER IRELAND LTD, 2020-08-01)BACKGROUND AND PURPOSE: Daily image guidance is standard care for prostate radiotherapy. Innovations which improve the accuracy and efficiency of ultrasound guidance are needed, particularly with respect to reducing ... -
Inclusion of a Charge Sharing Correction Algorithm Into an X-Ray Photon Counting Spectral Detector Simulation Framework
Pickford Scienti, OLP; Bamber, JC; Darambara, DG (IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 2021-07-01) -
Investigating the Contribution of Collagen to the Tumor Biomechanical Phenotype with Noninvasive Magnetic Resonance Elastography.
Li, J; Zormpas-Petridis, K; Boult, JKR; Reeves, EL; Heindl, A; et al. (AMER ASSOC CANCER RESEARCH, 2019-11-15)Increased stiffness in the extracellular matrix (ECM) contributes to tumor progression and metastasis. Therefore, stromal modulating therapies and accompanying biomarkers are being developed to target ECM stiffness. Magnetic ... -
Investigating the contribution of hyaluronan to the breast tumour microenvironment using multiparametric MRI and MR elastography.
Reeves, EL; Li, J; Zormpas-Petridis, K; Boult, JKR; Sullivan, J; et al. (WILEY, 2023-06-01)Hyaluronan (HA) is a key component of the dense extracellular matrix in breast cancer, and its accumulation is associated with poor prognosis and metastasis. Pegvorhyaluronidase alfa (PEGPH20) enzymatically degrades HA and ... -
Investigation of In Vivo skin stiffness anisotropy in breast cancer related lymphoedema.
Coutts, LV; Miller, NR; Mortimer, PS; Bamber, JC (ELSEVIER SCI LTD, 2016-01-04)There is a limited range of suitable measurement techniques for detecting and assessing breast cancer related lymphoedema (BCRL). This study investigated the suitability of using skin stiffness measurements, with a particular ... -
In Vivo Validation of Elekta's Clarity Autoscan for Ultrasound-based Intrafraction Motion Estimation of the Prostate During Radiation Therapy.
Grimwood, A; McNair, HA; O'Shea, TP; Gilroy, S; Thomas, K; et al. (ELSEVIER SCIENCE INC, 2018-11-15)PURPOSE: Our purpose was to perform an in vivo validation of ultrasound imaging for intrafraction motion estimation using the Elekta Clarity Autoscan system during prostate radiation therapy. The study was conducted as ... -
Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight.
Elyas, E; Grimwood, A; Erler, JT; Robinson, SP; Cox, TR; et al. (PUBLIC LIBRARY SCIENCE, 2017-01-20)Elastography, the imaging of elastic properties of soft tissues, is well developed for macroscopic clinical imaging of soft tissues and can provide useful information about various pathological processes which is complementary ... -
Near-infrared photoimmunotherapy targeting EGFR-Shedding new light on glioblastoma treatment.
Burley, TA; Mączyńska, J; Shah, A; Szopa, W; Harrington, KJ; et al. (WILEY, 2018-06-01)Glioblastomas (GBMs) are high-grade brain tumors, differentially driven by alterations (amplification, deletion or missense mutations) in the epidermal growth factor receptor (EGFR), that carry a poor prognosis of just ... -
Non-coplanar trajectories to improve organ at risk sparing in volumetric modulated arc therapy for primary brain tumors.
Smyth, G; Evans, PM; Bamber, JC; Mandeville, HC; Welsh, LC; et al. (ELSEVIER IRELAND LTD, 2016-10-01)BACKGROUND AND PURPOSE: To evaluate non-coplanar volumetric modulated arc radiotherapy (VMAT) trajectories for organ at risk (OAR) sparing in primary brain tumor radiotherapy. MATERIALS AND METHODS: Fifteen patients were ... -
On the Comparative Suitability of Strain Relaxation and Stress Relaxation Compression for Ultrasound Poroelastic Tissue Characterization
Theodorou, M; Fromageau, J; DeSouza, NM; Bamber, JC (FRONTIERS MEDIA SA, 2021-05-10)<jats:p>Poroelastic tissue strain imaging measures the time-varying and spatially varying deformation of a soft-tissue matrix during compression as the tissue fluid flows out of the compartmental boundaries. With the help ... -
Optically and acoustically triggerable sub-micron phase-change contrast agents for enhanced photoacoustic and ultrasound imaging.
Lin, S; Shah, A; Hernández-Gil, J; Stanziola, A; Harriss, BI; et al. (ELSEVIER GMBH, 2017-06-01)We demonstrate a versatile phase-change sub-micron contrast agent providing three modes of contrast enhancement: 1) photoacoustic imaging contrast, 2) ultrasound contrast with optical activation, and 3) ultrasound contrast ... -
Plane wave versus focused transmissions for contrast enhanced ultrasound imaging: the role of parameter settings and the effects of flow rate on contrast measurements.
Moghimirad, E; Bamber, J; Harris, E (IOP PUBLISHING LTD, 2019-04-23)Contrast enhanced ultrasound (CEUS) and dynamic contrast enhanced ultrasound (DCE-US) can be used to provide information about the vasculature aiding diagnosis and monitoring of a number of pathologies including cancer. ... -
Preclinical Three-Dimensional Vibrational Shear Wave Elastography for Mapping of Tumour Biomechanical Properties In Vivo.
Parasaram, V; Civale, J; Bamber, JC; Robinson, SP; Jamin, Y; et al. (MDPI, 2022-10-03)Preclinical investigation of the biomechanical properties of tissues and their treatment-induced changes are essential to support drug-discovery, clinical translation of biomarkers of treatment response, and studies of ... -
Quantitative photoacoustic imaging study of tumours in vivo: Baseline variations in quantitative measurements.
Martinho Costa, M; Shah, A; Rivens, I; Box, C; O'Shea, T; et al. (ELSEVIER GMBH, 2019-03-01)Photoacoustic imaging (PAI) provides information on haemoglobin levels and blood oxygenation (sO2). To facilitate assessment of the variability in sO2 and haemoglobin in tumours, for example in response to therapies, the ... -
Rapid scanning wide-field clutter elimination in epi-optoacoustic imaging using comb LOVIT.
Petrosyan, T; Theodorou, M; Bamber, J; Frenz, M; Jaeger, M (ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2018-06-01)Epi-style optoacoustic (OA) imaging provides flexibility by integrating the irradiation optics and ultrasound receiver, yet clutter generated by optical absorption near the probe obscures deep OA sources. Localised vibration ...