Browsing ICR Divisions by author "Liu, Manjuan"
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3‑nitrobenzanthrone Mirza, A; Arlt, VM; Meinl, W; Florian, S; Nagy, E; Barta, F; Thomann, M; Mrizova, I; Krais, AM; Liu, M; Richards, M; Kopka, K; Phillips, DH; Glatt, H; Stiborova, M; Schmeiser, HH
Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitution. Hayes, A; Mok, NY; Liu, M; Thai, C; Henley, AT; Atrash, B; Lanigan, RM; Sejberg, J; Le Bihan, Y-V; Bavetsias, V; Blagg, J; Raynaud, FI (2017-09)1. We have previously described C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-one derivatives as cell permeable inhibitors of the KDM4 and KDM5 subfamilies of JmjC histone lysine demethylases. 2. Although exemplar compound ...
Welford, AJ; Caldwell, JJ; Liu, M; Richards, M; Brown, N; Lomas, C; Tizzard, GJ; Pitak, MB; Coles, SJ; Eccles, SA; Raynaud, FI; Collins, I (2016-04)The 2,11-cembranoid family of natural products has been used as inspiration for the synthesis of a structurally simplified, functionally diverse library of octahydroisobenzofuran-based compounds designed to augment a typical ...