Browsing ICR Divisions by author "Hawkins, Elizabeth"
Now showing items 1-2 of 2
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Armored CAR T-Cells: The Next Chapter in T-Cell Cancer Immunotherapy.
Hawkins, ER; D'Souza, RR; Klampatsa, A (DOVE MEDICAL PRESS LTD, 2021-01-01)Chimeric antigen receptor (CAR) T-cell therapy engineers T-cells to express a synthetic receptor which redirects effector function to the tumor, to improve efficacy and reduce toxicities associated with conventional ... -
Overcoming tumor antigen heterogeneity in CAR-T cell therapy for malignant mesothelioma (MM)
D'Souza, RR; Dimou, P; Bughda, R; Hawkins, E; Babe, CL; et al. (OAE PUBLISHING INC, 2022-01-01)<jats:p>Malignant mesothelioma (MM) is a rare, aggressive solid tumor with limited therapeutic options and poor therapeutic response. The role of immunotherapy in MM is now well established and therapeutic options, such ...