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Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer.
BACKGROUND:Liquid biopsies have demonstrated that the constitutively active androgen receptor splice variant-7 (AR-V7) associates with reduced response and overall survival from endocrine therapies in castration-resistant ...
Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer.
BACKGROUND:Understanding the integrated immunogenomic landscape of advanced prostate cancer (APC) could impact stratified treatment selection. METHODS:Defective mismatch repair (dMMR) status was determined by either loss ...