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Impact of the cystic fibrosis mutation F508del-CFTR on renal cyst formation and growth.
(AMER PHYSIOLOGICAL SOC, 2012-10-15)
In autosomal dominant polycystic kidney disease (ADPKD), cystic fibrosis transmembrane conductance regulator (CFTR), the protein product of the gene defective in cystic fibrosis (CF), plays a crucial role in fluid accumulation, ...