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Urological referral of asymptomatic men in general practice in England
(NATURE PUBLISHING GROUP, 2008-04-01)
The Prostate Cancer Risk Management Programme (PCRMP) launched in November 2002 provides guidelines for general practitioners (GPs) on age-specific prostate-specific antigen (PSA) cutoff levels in asymptomatic men. The ...
Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders
(2008-03)
The European Myeloma Network (EMN) organized two flow cytometry workshops. The first aimed to identify specific indications for flow cytometry in patients with monoclonal gammopathies, and consensus technical approaches ...
An evaluation of the performance of HapMap SNP data in a Shanghai Chinese population: Analyses of allele frequency, linkage disequilibrium pattern and tagging SNPs transferability on chromosome Iq2I-q25
(2008-02)
Background: The HapMap project aimed to catalog millions of common single nucleotide polymorphisms ( SNPs) in the human genome in four major populations, in order to facilitate association studies of complex diseases. To ...
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: A case control study in an Italian population
(2008-05)
Background: Inherited genetic factors such as E-cadherin (CDH1) promoter variants are believed to influence the risk towards sporadic diffuse gastric cancer (DGC). Recently, a new regulatory region essential for CDH1 ...
Population screening for colorectal cancer: the implications of an ageing population
(NATURE PUBLISHING GROUP, 2008-12-09)
Population screening for colorectal cancer (CRC) has recently commenced in the United Kingdom supported by the evidence of a number of randomised trials and pilot studies. Certain factors are known to influence screening ...
A comparison between cobalt and linear accelerator-based treatment plans for conformal and intensity-modulated radiotherapy
(BRITISH INST RADIOLOGY, 2008-04)
The simplicity of cobalt units gives them the advantage ofreduced maintenance, running costs and downtime when compared with linear accelerators. However, treatments carried out on such units are typically limited to simple ...
Protein identification and quantification by two-dimensional infrared spectroscopy: Implications for an all-optical proteomic platform
(NATL ACAD SCIENCES, 2008-10-07)
Electron-vibration-vibration two-dimensional coherent spectroscopy, a variant of 2DIR, is shown to be a useful tool to differentiate a set of 10 proteins based on their amino acid content. Two-dimensional vibrational ...
The level of hypotension during hemorrhagic shock is a major determinant of the post-resuscitation systemic inflammatory response: an experimental study.
(Springer Science and Business Media LLC, 2008-07-18)
BACKGROUND: To evaluate whether the level of hypotension during hemorrhagic shock may influence the oxidative and inflammatory responses developed during post-ischemic resuscitation. METHODS: Fifteen rabbits were equally ...