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Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis
(BIOMED CENTRAL LTD, 2009-08)
Background: The availability of the complete chicken (Gallus gallus) genome sequence as well as a large number of chicken probes for fluorescent in-situ hybridization (FISH) and microarray resources facilitate comparative ...
Report of the European Myeloma Network on multiparametric flow cytometry in multiple myeloma and related disorders
(2008-03)
The European Myeloma Network (EMN) organized two flow cytometry workshops. The first aimed to identify specific indications for flow cytometry in patients with monoclonal gammopathies, and consensus technical approaches ...
Functional characterization of E- and P-cadherin in invasive breast cancer cells
(BIOMED CENTRAL LTD, 2009-03-03)
Background: Alterations in the cadherin-catenin adhesion complexes are involved in tumor initiation, progression and metastasis. However, the functional implication of distinct cadherin types in breast cancer biology is ...
Nonperturbative real-space renormalization group scheme for the spin-1/2 XXX Heisenberg model
(AMER PHYSICAL SOC, 2001-11-01)
In this paper we apply an analytical real-space renormalization group formulation which is based on numerical concepts of the density-matrix renormalization group, Within a rigorous mathematical framework we construct ...
Real time fluorescence imaging of PLC gamma translocation and its interaction with the epidermal growth factor receptor
(2001-04-30)
The translocation of fluorescently tagged PLC gamma and requirements for this process in cells stimulated with EGF were analyzed using real time fluorescence microscopy applied for the first time to monitor growth factor ...
Acetylation increases access of remodelling complexes to their nucleosome targets to enhance initiation of V(D)J recombination.
(2007-01)
Targeted chromatin remodelling is essential for many nuclear processes, including the regulation of V(D)J recombination. ATP-dependent nucleosome remodelling complexes are important players in this process whose activity ...
RNA editing of human microRNAs
(2006)
BACKGROUND: MicroRNAs (miRNAs) are short RNAs of around 22 nucleotides that regulate gene expression. The primary transcripts of miRNAs contain double-stranded RNA and are therefore potential substrates for adenosine to ...
Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential
(COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT, 2007-11-01)
Oncogenic mutations of the MLL histone methyltransferase confer an unusual ability to transform non-self-renewing myeloid progenitors into leukemia stem cells (LSCs) by mechanisms that remain poorly defined. Misregulation ...
Combinatorial effects of splice variants modulate function of Aiolos
(2007)
The transcription factor Aiolos ( also known as IKZF3), a member of the Ikaros family of zinc-finger proteins, plays an important role in the control of B lymphocyte differentiation and proliferation. Previously, multiple ...