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Now showing items 41-50 of 2023
Single dose prostate radiotherapy - a step too far?
(2021-04-21)
hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA.
(2021-11-17)
Gemcitabine or 5-fluorouracil (5-FU) based treatments can be selected for pancreatic cancer. Equilibrative nucleoside transporter 1 (hENT1) predicts adjuvant gemcitabine treatment benefit over 5-FU. Cytidine deaminase ...
The use of three-dimensional surface imaging and assessment of aesthetics in breast cancer surgery
(Institute of Cancer Research (University Of London), 2020-12-31)
Aesthetic outcome from breast cancer surgery influences long-term psychosocial wellbeing. There is no gold standard measure. An objective measure is required in order to communicate and compare results ultimately to raise ...
Immunological combination treatment holds the key to improving survival in pancreatic cancer.
(2020-11)
Advances in surgery, peri-operative care and systemic chemotherapy have not significantly improved the prognosis of pancreatic cancer for several decades. Early clinical trials of immunotherapy have yielded disappointing ...
Utilization of Poly(ADP-Ribose) Polymerase Inhibitors in Ovarian Cancer: A Retrospective Cohort Study of US Healthcare Claims Data.
(2021-11-02)
<h4>Introduction</h4>We aimed to characterize real-world utilization of poly(ADP-ribose) polymerase (PARP) inhibitors (PARPi) in women with ovarian cancer (OC).<h4>Methods</h4>This retrospective observational study of ...
Under-Treatment of Older Patients with Newly Diagnosed Epithelial Ovarian Cancer Remains an Issue.
(2021-02-25)
Older women with ovarian cancer have disproportionately poorer survival outcomes than their younger counterparts and receive less treatment. In order to understand where the gaps lie in the treatment of older patients, ...
Efficient Online 4D Magnetic Resonance Imaging
(IEEE COMPUTER SOC, 2021-01-01)
Local control and toxicity after hypofractionated accelerated palliative RT in breast cancer
(ELSEVIER IRELAND LTD, 2022-05-01)
How RhoGEFs drive triple negative breast cancer cell invasion through the activation of YAP and TAZ
(Institute of Cancer Research (University Of London), 2020-03-31)
Dynamical remodelling of the cytoskeleton is essential for triple negative breast cancer metastasis (TNBC). Cell shape is regulated by RhoGEFs which activate Rho GTPases resulting in changes in actin polymerisation, ...
Investigating the role of DTX3L in the replication stress response
(Institute of Cancer Research (University Of London), 2023-01-20)
DNA replication must be carried out with high fidelity to ensure accurate transfer of genetic information upon cell division. The mechanisms by which damage upon DNA is repaired are extensive and are increasingly well ...