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MoKCa database--mutations of kinases in cancer.
(OXFORD UNIV PRESS, 2009-01-01)
Members of the protein kinase family are amongst the most commonly mutated genes in human cancer, and both mutated and activated protein kinases have proved to be tractable targets for the development of new anticancer ...
Membrane type-1 matrix metalloproteinase activity is regulated by the endocytic collagen receptor Endo180.
(COMPANY OF BIOLOGISTS LTD, 2009-11-15)
The molecular interactions leading to organised, controlled extracellular matrix degradation are of central importance during growth, development and tissue repair, and when deregulated contribute to disease processes ...
Reasons of PEG failure to eliminate gastroesophageal reflux in mechanically ventilated patients.
(BAISHIDENG PUBLISHING GROUP INC, 2009-11-21)
AIM: To investigate factors predicting failure of percutaneous endoscopic gastrostomy (PEG) to eliminate gastroesophageal reflux (GER). METHODS: Twenty-nine consecutive mechanically ventilated patients were investigated. ...