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Cervical HPV infection and neoplasia in a large population-based prospective study: the Manchester cohort
(NATURE PUBLISHING GROUP, 2004-08-31)
Cytology and histology records and cervical samples for HPV assay were obtained from a prospective cohort of 49 655 women attending clinics for routine cervical cytology in or near Manchester between 1988 and 1993. The ...
A randomised comparison of UK genetic risk counselling services for familial cancer: psychosocial outcomes
(NATURE PUBLISHING GROUP, 2004-08-31)
The aim of the study was to compare psychosocial outcomes for 50 new clinic attendees, referred for cancer genetic counselling to five UK centres. The centres represented England, Scotland and Wales, and were randomly ...
Variation in RNA expression and genomic DNA content acquired during cell culture
(NATURE PUBLISHING GROUP, 2004-02-26)
Specific chromosomal abnormalities are increasingly recognised to be associated with particular tumour subtypes. These cytogenetic abnormalities define the sites of specific genes, the alteration of which is implicated in ...
Resveratrol inhibits benzo[a]pyrene-DNA adduct formation in human bronchial epithelial cells
(NATURE PUBLISHING GROUP, 2004-07-19)
Resveratrol ( trans-3,4’,5-trihydroxystilbene), a phytoalexin present in various plants and foods, has in several in vitro and in vivo studies demonstrated cancer chemopreventive and chemotherapeutic potential. We investigated ...
Should women under 50 be screened for breast cancer?
(NATURE PUBLISHING GROUP, 2004-08-02)
Despite some controversy in recent years, the majority of experts agree on the evidence for effectiveness of breast screening by mammography for women aged 50 years and above, but for those under 50 years, the picture is ...