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dc.contributor.authorSmids, Cen_US
dc.contributor.authorKouijzer, IJEen_US
dc.contributor.authorVos, FJen_US
dc.contributor.authorSprong, Ten_US
dc.contributor.authorHosman, AJFen_US
dc.contributor.authorde Rooy, JWJen_US
dc.contributor.authorAarntzen, EHJGen_US
dc.contributor.authorde Geus-Oei, L-Fen_US
dc.contributor.authorOyen, WJGen_US
dc.contributor.authorBleeker-Rovers, CPen_US
dc.date.accessioned2016-09-28T14:29:58Z
dc.date.issued2017-02en_US
dc.identifier.citationInfection, 2017, 45 (1), pp. 41 - 49en_US
dc.identifier.issn0300-8126en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/149
dc.identifier.eissn1439-0973en_US
dc.identifier.doi10.1007/s15010-016-0914-yen_US
dc.description.abstractThe purpose of this study was to evaluate the diagnostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT scan) and magnetic resonance imaging (MRI) in diagnosing spondylodiscitis and its complications, such as epidural and paraspinal abscesses.From January 2006 to August 2013 patients with a clinical suspicion of spondylodiscitis, with an infection, or with fever of unknown origin were retrospectively included if 18F-FDG-PET/CT and MRI of the spine were performed within a 2-week time span. Imaging results were compared to the final clinical diagnosis and follow-up data were collected.Sixty-eight patients were included of whom 49 patients were diagnosed with spondylodiscitis. MRI showed an overall sensitivity of 67 % and specificity of 84 %. Diagnostic accuracy was 58 %, when MRI was performed within 2 weeks after the start of symptoms and improved to 82 %, when performed more than 2 weeks after onset of symptoms. 18F-FDG-PET/CT showed a sensitivity of 96 % and a specificity of 95 %, with no relation to the interval between the scan and the start of symptoms.As compared to MRI, 18F-FDG-PET/CT has superior diagnostic value for detecting early spondylodiscitis. After 2 weeks both techniques perform similarly.en_US
dc.formatPrint-Electronicen_US
dc.format.extent41 - 49en_US
dc.languageengen_US
dc.language.isoengen_US
dc.subjectSpineen_US
dc.subjectHumansen_US
dc.subjectEpidural Abscessen_US
dc.subjectDiscitisen_US
dc.subjectFluorodeoxyglucose F18en_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectSensitivity and Specificityen_US
dc.subjectRetrospective Studiesen_US
dc.subjectAdolescenten_US
dc.subjectAdulten_US
dc.subjectAgeden_US
dc.subjectAged, 80 and overen_US
dc.subjectMiddle Ageden_US
dc.subjectChilden_US
dc.subjectFemaleen_US
dc.subjectMaleen_US
dc.subjectYoung Adulten_US
dc.subjectPositron Emission Tomography Computed Tomographyen_US
dc.titleA comparison of the diagnostic value of MRI and 18F-FDG-PET/CT in suspected spondylodiscitis.en_US
dc.typeJournal Article
dcterms.dateAccepted2016-06-03en_US
rioxxterms.versionofrecord10.1007/s15010-016-0914-yen_US
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0en_US
rioxxterms.licenseref.startdate2017-02en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfInfectionen_US
pubs.issue1en_US
pubs.notesNo embargoen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging
pubs.publication-statusPublisheden_US
pubs.volume45en_US
pubs.embargo.termsNo embargoen_US
icr.researchteamTranslational Molecular Imagingen_US
dc.contributor.icrauthorOyen, Willemen_US


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