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dc.contributor.authorSmids, C
dc.contributor.authorKouijzer, IJE
dc.contributor.authorVos, FJ
dc.contributor.authorSprong, T
dc.contributor.authorHosman, AJF
dc.contributor.authorde Rooy, JWJ
dc.contributor.authorAarntzen, EHJG
dc.contributor.authorde Geus-Oei, L-F
dc.contributor.authorOyen, WJG
dc.contributor.authorBleeker-Rovers, CP
dc.date.accessioned2016-09-28T14:29:58Z
dc.date.issued2017-02
dc.identifier.citationInfection, 2017, 45 (1), pp. 41 - 49
dc.identifier.issn0300-8126
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/149
dc.identifier.eissn1439-0973
dc.identifier.doi10.1007/s15010-016-0914-y
dc.description.abstractPurpose The purpose of this study was to evaluate the diagnostic value of 18 F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT scan) and magnetic resonance imaging (MRI) in diagnosing spondylodiscitis and its complications, such as epidural and paraspinal abscesses.Methods From January 2006 to August 2013 patients with a clinical suspicion of spondylodiscitis, with an infection, or with fever of unknown origin were retrospectively included if 18 F-FDG-PET/CT and MRI of the spine were performed within a 2-week time span. Imaging results were compared to the final clinical diagnosis and follow-up data were collected.Results Sixty-eight patients were included of whom 49 patients were diagnosed with spondylodiscitis. MRI showed an overall sensitivity of 67 % and specificity of 84 %. Diagnostic accuracy was 58 %, when MRI was performed within 2 weeks after the start of symptoms and improved to 82 %, when performed more than 2 weeks after onset of symptoms. 18 F-FDG-PET/CT showed a sensitivity of 96 % and a specificity of 95 %, with no relation to the interval between the scan and the start of symptoms.Conclusions As compared to MRI, 18 F-FDG-PET/CT has superior diagnostic value for detecting early spondylodiscitis. After 2 weeks both techniques perform similarly.
dc.formatPrint-Electronic
dc.format.extent41 - 49
dc.languageeng
dc.language.isoeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectSpine
dc.subjectHumans
dc.subjectEpidural Abscess
dc.subjectDiscitis
dc.subjectFluorodeoxyglucose F18
dc.subjectMagnetic Resonance Imaging
dc.subjectSensitivity and Specificity
dc.subjectRetrospective Studies
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectMiddle Aged
dc.subjectChild
dc.subjectFemale
dc.subjectMale
dc.subjectYoung Adult
dc.subjectPositron Emission Tomography Computed Tomography
dc.titleA comparison of the diagnostic value of MRI and 18 F-FDG-PET/CT in suspected spondylodiscitis.
dc.typeJournal Article
dcterms.dateAccepted2016-06-03
rioxxterms.versionofrecord10.1007/s15010-016-0914-y
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2017-02
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfInfection
pubs.issue1
pubs.notesNo embargo
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging
pubs.publication-statusPublished
pubs.volume45
pubs.embargo.termsNo embargo
icr.researchteamTranslational Molecular Imagingen_US
dc.contributor.icrauthorOyen, Willemen


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