dc.contributor.author | Smids, C | |
dc.contributor.author | Kouijzer, IJE | |
dc.contributor.author | Vos, FJ | |
dc.contributor.author | Sprong, T | |
dc.contributor.author | Hosman, AJF | |
dc.contributor.author | de Rooy, JWJ | |
dc.contributor.author | Aarntzen, EHJG | |
dc.contributor.author | de Geus-Oei, L-F | |
dc.contributor.author | Oyen, WJG | |
dc.contributor.author | Bleeker-Rovers, CP | |
dc.date.accessioned | 2016-09-28T14:29:58Z | |
dc.date.issued | 2017-02 | |
dc.identifier.citation | Infection, 2017, 45 (1), pp. 41 - 49 | |
dc.identifier.issn | 0300-8126 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/149 | |
dc.identifier.eissn | 1439-0973 | |
dc.identifier.doi | 10.1007/s15010-016-0914-y | |
dc.description.abstract | Purpose The purpose of this study was to evaluate the diagnostic value of 18 F-fluorodeoxyglucose (FDG) positron emission tomography and computed tomography (PET/CT scan) and magnetic resonance imaging (MRI) in diagnosing spondylodiscitis and its complications, such as epidural and paraspinal abscesses.Methods From January 2006 to August 2013 patients with a clinical suspicion of spondylodiscitis, with an infection, or with fever of unknown origin were retrospectively included if 18 F-FDG-PET/CT and MRI of the spine were performed within a 2-week time span. Imaging results were compared to the final clinical diagnosis and follow-up data were collected.Results Sixty-eight patients were included of whom 49 patients were diagnosed with spondylodiscitis. MRI showed an overall sensitivity of 67 % and specificity of 84 %. Diagnostic accuracy was 58 %, when MRI was performed within 2 weeks after the start of symptoms and improved to 82 %, when performed more than 2 weeks after onset of symptoms. 18 F-FDG-PET/CT showed a sensitivity of 96 % and a specificity of 95 %, with no relation to the interval between the scan and the start of symptoms.Conclusions As compared to MRI, 18 F-FDG-PET/CT has superior diagnostic value for detecting early spondylodiscitis. After 2 weeks both techniques perform similarly. | |
dc.format | Print-Electronic | |
dc.format.extent | 41 - 49 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.subject | Spine | |
dc.subject | Humans | |
dc.subject | Epidural Abscess | |
dc.subject | Discitis | |
dc.subject | Fluorodeoxyglucose F18 | |
dc.subject | Magnetic Resonance Imaging | |
dc.subject | Sensitivity and Specificity | |
dc.subject | Retrospective Studies | |
dc.subject | Adolescent | |
dc.subject | Adult | |
dc.subject | Aged | |
dc.subject | Aged, 80 and over | |
dc.subject | Middle Aged | |
dc.subject | Child | |
dc.subject | Female | |
dc.subject | Male | |
dc.subject | Young Adult | |
dc.subject | Positron Emission Tomography Computed Tomography | |
dc.title | A comparison of the diagnostic value of MRI and 18 F-FDG-PET/CT in suspected spondylodiscitis. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2016-06-03 | |
rioxxterms.versionofrecord | 10.1007/s15010-016-0914-y | |
rioxxterms.licenseref.uri | https://creativecommons.org/licenses/by/4.0 | |
rioxxterms.licenseref.startdate | 2017-02 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | Infection | |
pubs.issue | 1 | |
pubs.notes | No embargo | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging | |
pubs.publication-status | Published | |
pubs.volume | 45 | |
pubs.embargo.terms | No embargo | |
icr.researchteam | Translational Molecular Imaging | en_US |
dc.contributor.icrauthor | Oyen, Willem | |