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dc.contributor.authorHalling-Brown, MDen_US
dc.contributor.authorBulusu, KCen_US
dc.contributor.authorPatel, Men_US
dc.contributor.authorTym, JEen_US
dc.contributor.authorAl-Lazikani, Ben_US
dc.date.accessioned2018-06-28T14:43:45Z
dc.date.issued2012-01en_US
dc.identifier.citationNucleic acids research, 2012, 40 (Database issue), pp. D947 - D956en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/1967
dc.identifier.eissn1362-4962en_US
dc.identifier.doi10.1093/nar/gkr881en_US
dc.description.abstractcanSAR is a fully integrated cancer research and drug discovery resource developed to utilize the growing publicly available biological annotation, chemical screening, RNA interference screening, expression, amplification and 3D structural data. Scientists can, in a single place, rapidly identify biological annotation of a target, its structural characterization, expression levels and protein interaction data, as well as suitable cell lines for experiments, potential tool compounds and similarity to known drug targets. canSAR has, from the outset, been completely use-case driven which has dramatically influenced the design of the back-end and the functionality provided through the interfaces. The Web interface at http://cansar.icr.ac.uk provides flexible, multipoint entry into canSAR. This allows easy access to the multidisciplinary data within, including target and compound synopses, bioactivity views and expert tools for chemogenomic, expression and protein interaction network data.en_US
dc.formatPrint-Electronicen_US
dc.format.extentD947 - D956en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectCell Line, Tumoren_US
dc.subjectHumansen_US
dc.subjectNeoplasmsen_US
dc.subjectAntineoplastic Agentsen_US
dc.subjectGene Expressionen_US
dc.subjectRNA Interferenceen_US
dc.subjectModels, Molecularen_US
dc.subjectSystems Integrationen_US
dc.subjectInterneten_US
dc.subjectDatabases, Geneticen_US
dc.subjectGenetic Variationen_US
dc.subjectDrug Discoveryen_US
dc.subjectTranslational Medical Researchen_US
dc.subjectProtein Interaction Mapsen_US
dc.titlecanSAR: an integrated cancer public translational research and drug discovery resource.en_US
dc.typeJournal Article
rioxxterms.versionofrecord10.1093/nar/gkr881en_US
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc/4.0en_US
rioxxterms.licenseref.startdate2012-01en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfNucleic acids researchen_US
pubs.issueDatabase issueen_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Computational Biology and Chemogenomics
pubs.publication-statusPublisheden_US
pubs.volume40en_US
pubs.embargo.termsNot knownen_US
icr.researchteamComputational Biology and Chemogenomicsen_US
dc.contributor.icrauthorAl-Lazikani, Bissanen_US
dc.contributor.icrauthorBulusu, Krishnaen_US


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