Browsing Breast Cancer Research by author "Dowsett, Mitch"
Now showing items 41-45 of 45
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The prognostic effects of somatic mutations in ER-positive breast cancer.
Griffith, OL; Spies, NC; Anurag, M; Griffith, M; Luo, J; et al. (2018-09-04)Here we report targeted sequencing of 83 genes using DNA from primary breast cancer samples from 625 postmenopausal (UBC-TAM series) and 328 premenopausal (MA12 trial) hormone receptor-positive (HR+) patients to determine ... -
Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations.
Dowling, RJO; Kalinsky, K; Hayes, DF; Bidard, F-C; Cescon, DW; et al. (2019-12)Disease recurrence (locoregional, distant) exerts a significant clinical impact on the survival of estrogen receptor-positive breast cancer patients. Many of these recurrences occur late, more than 5 years after original ... -
Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions.
Dowling, RJO; Sparano, JA; Goodwin, PJ; Bidard, F-C; Cescon, DW; et al. (2019-12)Late disease recurrence (more than 5 years after initial diagnosis) represents a clinical challenge in the treatment and management of estrogen receptor-positive breast cancer (BC). An international workshop was convened ... -
TransHERA: The cell cycle regulator p27 predicts benefit from trastuzumab treatment in HER2-positive early breast cancer patients treated within the HERA trial
Filipits, M; Gnant, M; Dafni, U; Polydoropoulou, V; Hills, MJ; et al. (AMER ASSOC CANCER RESEARCH, 2015-05-01) -
Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial.
Cuzick, J; Sestak, I; Forbes, JF; Dowsett, M; Cawthorn, S; et al. (2020-01)BACKGROUND:Two large clinical trials have shown a reduced rate of breast cancer development in high-risk women in the initial 5 years of follow-up after use of aromatase inhibitors (MAP.3 and International Breast Cancer ...