Recent submissions

  • The Intracranial Distribution of Gliomas in Relation to Exposure From Mobile Phones: Analyses From the INTERPHONE Study. 

    Grell, K; Frederiksen, K; Schüz, J; Cardis, E; Armstrong, B; Siemiatycki, J; Krewski, DR; McBride, ML; Johansen, C; Auvinen, A; Hours, M; Blettner, M; Sadetzki, S; Lagorio, S; Yamaguchi, N; Woodward, A; Tynes, T; Feychting, M; Fleming, SJ; Swerdlow, AJ; Andersen, PK (2016-12-01)
    When investigating the association between brain tumors and use of mobile telephones, accurate data on tumor position are essential, due to the highly localized absorption of energy in the human brain from the radio-frequency ...
  • Cell-type-specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes. 

    Zhang, T; Choi, J; Kovacs, MA; Shi, J; Xu, M; NISC Comparative Sequencing Program; Melanoma Meta-Analysis Consortium; Goldstein, AM; Trower, AJ; Bishop, DT; Iles, MM; Duffy, DL; MacGregor, S; Amundadottir, LT; Law, MH; Loftus, SK; Pavan, WJ; Brown, KM (2018-11)
    Most expression quantitative trait locus (eQTL) studies to date have been performed in heterogeneous tissues as opposed to specific cell types. To better understand the cell-type-specific regulatory landscape of human ...
  • A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk. 

    Lu, Y; Beeghly-Fadiel, A; Wu, L; Guo, X; Li, B; Schildkraut, JM; Im, HK; Chen, YA; Permuth, JB; Reid, BM; Teer, JK; Moysich, KB; Andrulis, IL; Anton-Culver, H; Arun, BK; Bandera, EV; Barkardottir, RB; Barnes, DR; Benitez, J; Bjorge, L; Brenton, J; Butzow, R; Caldes, T; Caligo, MA; Campbell, I; Chang-Claude, J; Claes, KBM; Couch, FJ; Cramer, DW; Daly, MB; deFazio, A; Dennis, J; Diez, O; Domchek, SM; Dörk, T; Easton, DF; Eccles, DM; Fasching, PA; Fortner, RT; Fountzilas, G; Friedman, E; Ganz, PA; Garber, J; Giles, GG; Godwin, AK; Goldgar, DE; Goodman, MT; Greene, MH; Gronwald, J; Hamann, U; Heitz, F; Hildebrandt, MAT; Høgdall, CK; Hollestelle, A; Hulick, PJ; Huntsman, DG; Imyanitov, EN; Isaacs, C; Jakubowska, A; James, P; Karlan, BY; Kelemen, LE; Kiemeney, LA; Kjaer, SK; Kwong, A; Le, ND; Leslie, G; Lesueur, F; Levine, DA; Mattiello, A; May, T; McGuffog, L; McNeish, IA; Merritt, MA; Modugno, F; Montagna, M; Neuhausen, SL; Nevanlinna, H; Nielsen, FC; Nikitina-Zake, L; Nussbaum, RL; Offit, K; Olah, E; Olopade, OI; Olson, SH; Olsson, H; Osorio, A; Park, SK; Parsons, MT; Peeters, PHM; Pejovic, T; Peterlongo, P; Phelan, CM; Pujana, MA; Ramus, SJ; Rennert, G; Risch, H; Rodriguez, GC; Rodríguez-Antona, C; Romieu, I; Rookus, MA; Rossing, MA; Rzepecka, IK; Sandler, DP; Schmutzler, RK; Setiawan, VW; Sharma, P; Sieh, W; Simard, J; Singer, CF; Song, H; Southey, MC; Spurdle, AB; Sutphen, R; Swerdlow, AJ; Teixeira, MR; Teo, SH; Thomassen, M; Tischkowitz, M; Toland, AE; Trichopoulou, A; Tung, N; Tworoger, SS; van Rensburg, EJ; Vanderstichele, A; Vega, A; Edwards, DV; Webb, PM; Weitzel, JN; Wentzensen, N; White, E; Wolk, A; Wu, AH; Yannoukakos, D; Zorn, KK; Gayther, SA; Antoniou, AC; Berchuck, A; Goode, EL; Chenevix-Trench, G; Sellers, TA; Pharoah, PDP; Zheng, W; Long, J (2018-09-15)
    Large-scale genome-wide association studies (GWAS) have identified approximately 35 loci associated with epithelial ovarian cancer (EOC) risk. The majority of GWAS-identified disease susceptibility variants are located in ...
  • Brain and Salivary Gland Tumors and Mobile Phone Use: Evaluating the Evidence from Various Epidemiological Study Designs. 

    Röösli, M; Lagorio, S; Schoemaker, MJ; Schüz, J; Feychting, M (2019-01-11)
    Mobile phones (MPs) are the most relevant source of radiofrequency electromagnetic field (RF-EMF) exposure to the brain and the salivary gland. Whether this exposure implies a cancer risk has been addressed in several ...
  • Transcriptome-wide association study identifies new candidate susceptibility genes for glioma. 

    Atkins, I; Kinnersley, B; Ostrom, QT; Labreche, K; Il'yasova, D; Armstrong, GN; Eckel-Passow, JE; Schoemaker, MJ; Nöthen, MM; Barnholtz-Sloan, JS; Swerdlow, AJ; Simon, M; Rajaraman, P; Chanock, SJ; Shildkraut, J; Bernstein, JL; Hoffmann, P; Jöckel, K-H; Lai, RK; Claus, EB; Olson, SH; Johansen, C; Wrensch, MR; Melin, B; Jenkins, RB; Sanson, M; Bondy, ML; Houlston, RS (2019-02-01)
    Genome-wide association studies (GWAS) have so far identified 25 loci associated with glioma risk, with most showing specificity for either glioblastoma (GBM) or non-GBM tumors. The majority of these GWAS susceptibility ...
  • Genome-wide association study of anti-Müllerian hormone levels in pre-menopausal women of late reproductive age and relationship with genetic determinants of reproductive lifespan. 

    Ruth, KS; Soares, ALG; Borges, M-C; Eliassen, AH; Hankinson, SE; Jones, ME; Kraft, P; Nichols, HB; Sandler, DP; Schoemaker, MJ; Taylor, JA; Zeleniuch-Jacquotte, A; Lawlor, DA; Swerdlow, AJ; Murray, A (2019-01-14)
    Anti-Müllerian hormone (AMH) is required for sexual differentiation in the fetus, and in adult females AMH is produced by growing ovarian follicles. Consequently, AMH levels are correlated with ovarian reserve, declining ...
  • Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer. 

    Buus, R; Yeo, B; Brentnall, AR; Klintman, M; Cheang, MCU; Khabra, K; Sestak, I; Gao, Q; Cuzick, J; Dowsett, M (2018-09-04)
    BACKGROUND: Several prognostic signatures for early oestrogen receptor-positive (ER+) breast cancer have been established with a 10-year follow-up. We tested the hypothesis that signatures optimised for 0-5-year and 5-10-year ...
  • Shared heritability and functional enrichment across six solid cancers. 

    Jiang, X; Finucane, HK; Schumacher, FR; Schmit, SL; Tyrer, JP; Han, Y; Michailidou, K; Lesseur, C; Kuchenbaecker, KB; Dennis, J; Conti, DV; Casey, G; Gaudet, MM; Huyghe, JR; Albanes, D; Aldrich, MC; Andrew, AS; Andrulis, IL; Anton-Culver, H; Antoniou, AC; Antonenkova, NN; Arnold, SM; Aronson, KJ; Arun, BK; Bandera, EV; Barkardottir, RB; Barnes, DR; Batra, J; Beckmann, MW; Benitez, J; Benlloch, S; Berchuck, A; Berndt, SI; Bickeböller, H; Bien, SA; Blomqvist, C; Boccia, S; Bogdanova, NV; Bojesen, SE; Bolla, MK; Brauch, H; Brenner, H; Brenton, JD; Brook, MN; Brunet, J; Brunnström, H; Buchanan, DD; Burwinkel, B; Butzow, R; Cadoni, G; Caldés, T; Caligo, MA; Campbell, I; Campbell, PT; Cancel-Tassin, G; Cannon-Albright, L; Campa, D; Caporaso, N; Carvalho, AL; Chan, AT; Chang-Claude, J; Chanock, SJ; Chen, C; Christiani, DC; Claes, KBM; Claessens, F; Clements, J; Collée, JM; Correa, MC; Couch, FJ; Cox, A; Cunningham, JM; Cybulski, C; Czene, K; Daly, MB; deFazio, A; Devilee, P; Diez, O; Gago-Dominguez, M; Donovan, JL; Dörk, T; Duell, EJ; Dunning, AM; Dwek, M; Eccles, DM; Edlund, CK; Edwards, DRV; Ellberg, C; Evans, DG; Fasching, PA; Ferris, RL; Liloglou, T; Figueiredo, JC; Fletcher, O; Fortner, RT; Fostira, F; Franceschi, S; Friedman, E; Gallinger, SJ; Ganz, PA; Garber, J; García-Sáenz, JA; Gayther, SA; Giles, GG; Godwin, AK; Goldberg, MS; Goldgar, DE; Goode, EL; Goodman, MT; Goodman, G; Grankvist, K; Greene, MH; Gronberg, H; Gronwald, J; Guénel, P; Håkansson, N; Hall, P; Hamann, U; Hamdy, FC; Hamilton, RJ; Hampe, J; Haugen, A; Heitz, F; Herrero, R; Hillemanns, P; Hoffmeister, M; Høgdall, E; Hong, Y-C; Hopper, JL; Houlston, R; Hulick, PJ; Hunter, DJ; Huntsman, DG; Idos, G; Imyanitov, EN; Ingles, SA; Isaacs, C; Jakubowska, A; James, P; Jenkins, MA; Johansson, M; Johansson, M; John, EM; Joshi, AD; Kaneva, R; Karlan, BY; Kelemen, LE; Kühl, T; Khaw, K-T; Khusnutdinova, E; Kibel, AS; Kiemeney, LA; Kim, J; Kjaer, SK; Knight, JA; Kogevinas, M; Kote-Jarai, Z; Koutros, S; Kristensen, VN; Kupryjanczyk, J; Lacko, M; Lam, S; Lambrechts, D; Landi, MT; Lazarus, P; Le, ND; Lee, E; Lejbkowicz, F; Lenz, H-J; Leslie, G; Lessel, D; Lester, J; Levine, DA; Li, L; Li, CI; Lindblom, A; Lindor, NM; Liu, G; Loupakis, F; Lubiński, J; Maehle, L; Maier, C; Mannermaa, A; Marchand, LL; Margolin, S; May, T; McGuffog, L; Meindl, A; Middha, P; Miller, A; Milne, RL; MacInnis, RJ; Modugno, F; Montagna, M; Moreno, V; Moysich, KB; Mucci, L; Muir, K; Mulligan, AM; Nathanson, KL; Neal, DE; Ness, AR; Neuhausen, SL; Nevanlinna, H; Newcomb, PA; Newcomb, LF; Nielsen, FC; Nikitina-Zake, L; Nordestgaard, BG; Nussbaum, RL; Offit, K; Olah, E; Olama, AAA; Olopade, OI; Olshan, AF; Olsson, H; Osorio, A; Pandha, H; Park, JY; Pashayan, N; Parsons, MT; Pejovic, T; Penney, KL; Peters, WHM; Phelan, CM; Phipps, AI; Plaseska-Karanfilska, D; Pring, M; Prokofyeva, D; Radice, P; Stefansson, K; Ramus, SJ; Raskin, L; Rennert, G; Rennert, HS; van Rensburg, EJ; Riggan, MJ; Risch, HA; Risch, A; Roobol, MJ; Rosenstein, BS; Rossing, MA; De Ruyck, K; Saloustros, E; Sandler, DP; Sawyer, EJ; Schabath, MB; Schleutker, J; Schmidt, MK; Setiawan, VW; Shen, H; Siegel, EM; Sieh, W; Singer, CF; Slattery, ML; Sorensen, KD; Southey, MC; Spurdle, AB; Stanford, JL; Stevens, VL; Stintzing, S; Stone, J; Sundfeldt, K; Sutphen, R; Swerdlow, AJ; Tajara, EH; Tangen, CM; Tardon, A; Taylor, JA; Teare, MD; Teixeira, MR; Terry, MB; Terry, KL; Thibodeau, SN; Thomassen, M; Bjørge, L; Tischkowitz, M; Toland, AE; Torres, D; Townsend, PA; Travis, RC; Tung, N; Tworoger, SS; Ulrich, CM; Usmani, N; Vachon, CM; Van Nieuwenhuysen, E; Vega, A; Aguado-Barrera, ME; Wang, Q; Webb, PM; Weinberg, CR; Weinstein, S; Weissler, MC; Weitzel, JN; West, CML; White, E; Whittemore, AS; Wichmann, H-E; Wiklund, F; Winqvist, R; Wolk, A; Woll, P; Woods, M; Wu, AH; Wu, X; Yannoukakos, D; Zheng, W; Zienolddiny, S; Ziogas, A; Zorn, KK; Lane, JM; Saxena, R; Thomas, D; Hung, RJ; Diergaarde, B; McKay, J; Peters, U; Hsu, L; García-Closas, M; Eeles, RA; Chenevix-Trench, G; Brennan, PJ; Haiman, CA; Simard, J; Easton, DF; Gruber, SB; Pharoah, PDP; Price, AL; Pasaniuc, B; Amos, CI; Kraft, P; Lindström, S (2019-01-25)
    Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total ...
  • Genetic susceptibility to radiation-induced breast cancer after Hodgkin Lymphoma. 

    Opstal-van Winden, AWJ; de Haan, HG; Hauptmann, M; Schmidt, MK; Broeks, A; Russell, NS; Janus, CPM; Krol, ADG; van der Baan, FH; De Bruin, ML; van Eggermond, AM; Dennis, J; Anton Culver, H; Haiman, CA; Sawyer, EJ; Cox, A; Devilee, P; Hooning, MJ; Peto, J; Couch, FJ; Pharoah, P; Orr, N; Easton, DF; Aleman, BMP; Strong, LC; Bhatia, S; Cooke, R; Robison, LL; Swerdlow, AJ; van Leeuwen, FE (2018-12-20)
    Female Hodgkin lymphoma (HL) patients treated with chest radiotherapy (RT) have a very high risk of breast cancer. The contribution of genetic factors to this risk is unclear. We therefore examined 211,155 germline single ...
  • A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells. 

    Domenici, G; Aurrekoetxea-Rodríguez, I; Simões, BM; Rábano, M; Lee, SY; Millán, JS; Comaills, V; Oliemuller, E; López-Ruiz, JA; Zabalza, I; Howard, BA; Kypta, RM; Vivanco, MD (2019-01-08)
    Increased cancer stem cell content during development of resistance to tamoxifen in breast cancer is driven by multiple signals, including Sox2-dependent activation of Wnt signalling. Here, we show that Sox2 increases and ...
  • Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma. 

    Went, M; Sud, A; Försti, A; Halvarsson, B-M; Weinhold, N; Kimber, S; van Duin, M; Thorleifsson, G; Holroyd, A; Johnson, DC; Li, N; Orlando, G; Law, PJ; Ali, M; Chen, B; Mitchell, JS; Gudbjartsson, DF; Kuiper, R; Stephens, OW; Bertsch, U; Broderick, P; Campo, C; Bandapalli, OR; Einsele, H; Gregory, WA; Gullberg, U; Hillengass, J; Hoffmann, P; Jackson, GH; Jöckel, K-H; Johnsson, E; Kristinsson, SY; Mellqvist, U-H; Nahi, H; Easton, D; Pharoah, P; Dunning, A; Peto, J; Canzian, F; Swerdlow, A; Eeles, RA; Kote-Jarai, Z; Muir, K; Pashayan, N; PRACTICAL consortium; Nickel, J; Nöthen, MM; Rafnar, T; Ross, FM; da Silva Filho, MI; Thomsen, H; Turesson, I; Vangsted, A; Andersen, NF; Waage, A; Walker, BA; Wihlborg, A-K; Broyl, A; Davies, FE; Thorsteinsdottir, U; Langer, C; Hansson, M; Goldschmidt, H; Kaiser, M; Sonneveld, P; Stefansson, K; Morgan, GJ; Hemminki, K; Nilsson, B; Houlston, RS (2019-01-10)
    The original version of this Article contained an error in the spelling of a member of the PRACTICAL Consortium, Manuela Gago-Dominguez, which was incorrectly given as Manuela Gago Dominguez. This has now been corrected ...
  • Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival. 

    Oser, MG; Fonseca, R; Chakraborty, AA; Brough, R; Spektor, A; Jennings, RB; Flaifel, A; Novak, JS; Gulati, A; Buss, E; Younger, ST; McBrayer, SK; Cowley, GS; Bonal, DM; Nguyen, Q-D; Brulle-Soumare, L; Taylor, P; Cairo, S; Ryan, CJ; Pease, EJ; Maratea, K; Travers, J; Root, DE; Signoretti, S; Pellman, D; Ashton, S; Lord, CJ; Barry, ST; Kaelin, WG (2018-10-29)
    Small cell lung cancer (SCLC) accounts for 15% of lung cancers and is almost always linked to inactivating RB1 and TP53 mutations. SCLC frequently responds, albeit briefly, to chemotherapy. The canonical function of the ...
  • Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent. 

    Guo, Y; Warren Andersen, S; Shu, X-O; Michailidou, K; Bolla, MK; Wang, Q; Garcia-Closas, M; Milne, RL; Schmidt, MK; Chang-Claude, J; Dunning, A; Bojesen, SE; Ahsan, H; Aittomäki, K; Andrulis, IL; Anton-Culver, H; Arndt, V; Beckmann, MW; Beeghly-Fadiel, A; Benitez, J; Bogdanova, NV; Bonanni, B; Børresen-Dale, A-L; Brand, J; Brauch, H; Brenner, H; Brüning, T; Burwinkel, B; Casey, G; Chenevix-Trench, G; Couch, FJ; Cox, A; Cross, SS; Czene, K; Devilee, P; Dörk, T; Dumont, M; Fasching, PA; Figueroa, J; Flesch-Janys, D; Fletcher, O; Flyger, H; Fostira, F; Gammon, M; Giles, GG; Guénel, P; Haiman, CA; Hamann, U; Hooning, MJ; Hopper, JL; Jakubowska, A; Jasmine, F; Jenkins, M; John, EM; Johnson, N; Jones, ME; Kabisch, M; Kibriya, M; Knight, JA; Koppert, LB; Kosma, V-M; Kristensen, V; Le Marchand, L; Lee, E; Li, J; Lindblom, A; Luben, R; Lubinski, J; Malone, KE; Mannermaa, A; Margolin, S; Marme, F; McLean, C; Meijers-Heijboer, H; Meindl, A; Neuhausen, SL; Nevanlinna, H; Neven, P; Olson, JE; Perez, JIA; Perkins, B; Peterlongo, P; Phillips, K-A; Pylkäs, K; Rudolph, A; Santella, R; Sawyer, EJ; Schmutzler, RK; Seynaeve, C; Shah, M; Shrubsole, MJ; Southey, MC; Swerdlow, AJ; Toland, AE; Tomlinson, I; Torres, D; Truong, T; Ursin, G; Van Der Luijt, RB; Verhoef, S; Whittemore, AS; Winqvist, R; Zhao, H; Zhao, S; Hall, P; Simard, J; Kraft, P; Pharoah, P; Hunter, D; Easton, DF; Zheng, W (2016-08)
    BACKGROUND: Observational epidemiological studies have shown that high body mass index (BMI) is associated with a reduced risk of breast cancer in premenopausal women but an increased risk in postmenopausal women. It is ...
  • Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers. 

    Schmidt, MK; Hogervorst, F; van Hien, R; Cornelissen, S; Broeks, A; Adank, MA; Meijers, H; Waisfisz, Q; Hollestelle, A; Schutte, M; van den Ouweland, A; Hooning, M; Andrulis, IL; Anton-Culver, H; Antonenkova, NN; Antoniou, AC; Arndt, V; Bermisheva, M; Bogdanova, NV; Bolla, MK; Brauch, H; Brenner, H; Brüning, T; Burwinkel, B; Chang-Claude, J; Chenevix-Trench, G; Couch, FJ; Cox, A; Cross, SS; Czene, K; Dunning, AM; Fasching, PA; Figueroa, J; Fletcher, O; Flyger, H; Galle, E; García-Closas, M; Giles, GG; Haeberle, L; Hall, P; Hillemanns, P; Hopper, JL; Jakubowska, A; John, EM; Jones, M; Khusnutdinova, E; Knight, JA; Kosma, V-M; Kristensen, V; Lee, A; Lindblom, A; Lubinski, J; Mannermaa, A; Margolin, S; Meindl, A; Milne, RL; Muranen, TA; Newcomb, PA; Offit, K; Park-Simon, T-W; Peto, J; Pharoah, PDP; Robson, M; Rudolph, A; Sawyer, EJ; Schmutzler, RK; Seynaeve, C; Soens, J; Southey, MC; Spurdle, AB; Surowy, H; Swerdlow, A; Tollenaar, RAEM; Tomlinson, I; Trentham-Dietz, A; Vachon, C; Wang, Q; Whittemore, AS; Ziogas, A; van der Kolk, L; Nevanlinna, H; Dörk, T; Bojesen, S; Easton, DF (2016-08-10)
    PURPOSE: CHEK2*1100delC is a well-established breast cancer risk variant that is most prevalent in European populations; however, there are limited data on risk of breast cancer by age and tumor subtype, which limits its ...
  • Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer. 

    Painter, JN; O'Mara, TA; Marquart, L; Webb, PM; Attia, J; Medland, SE; Cheng, T; Dennis, J; Holliday, EG; McEvoy, M; Scott, RJ; Ahmed, S; Healey, CS; Shah, M; Gorman, M; Martin, L; Hodgson, SV; Beckmann, MW; Ekici, AB; Fasching, PA; Hein, A; Rübner, M; Czene, K; Darabi, H; Hall, P; Li, J; Dörk, T; Dürst, M; Hillemanns, P; Runnebaum, IB; Amant, F; Annibali, D; Depreeuw, J; Lambrechts, D; Neven, P; Cunningham, JM; Dowdy, SC; Goode, EL; Fridley, BL; Winham, SJ; Njølstad, TS; Salvesen, HB; Trovik, J; Werner, HMJ; Ashton, KA; Otton, G; Proietto, A; Mints, M; Tham, E; Bolla, MK; Michailidou, K; Wang, Q; Tyrer, JP; Hopper, JL; Peto, J; Swerdlow, AJ; Burwinkel, B; Brenner, H; Meindl, A; Brauch, H; Lindblom, A; Chang-Claude, J; Couch, FJ; Giles, GG; Kristensen, VN; Cox, A; Pharoah, PDP; Tomlinson, I; Dunning, AM; Easton, DF; Thompson, DJ; Spurdle, AB; AOCS Group; for RENDOCAS; National Study of Endometrial Cancer Genetics Group (NSECG); Australian National Endometrial Cancer Study Group (ANECS) (2016-11)
    BACKGROUND: The strongest known risk factor for endometrial cancer is obesity. To determine whether SNPs associated with increased body mass index (BMI) or waist-hip ratio (WHR) are associated with endometrial cancer risk, ...
  • Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain. 

    Kijewska, M; Viski, C; Turrell, F; Fitzpatrick, A; van Weverwijk, A; Gao, Q; Iravani, M; Isacke, CM (2019-01-14)
    BACKGROUND: Dissemination of breast cancers to the brain is associated with poor patient outcome and limited therapeutic options. In this study we sought to identify novel regulators of brain metastasis by profiling mouse ...
  • Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk. 

    Yang, Y; Wu, L; Shu, X; Lu, Y; Shu, X-O; Cai, Q; Beeghly-Fadiel, A; Li, B; Ye, F; Berchuck, A; Anton-Culver, H; Banerjee, S; Benitez, J; Bjørge, L; Brenton, JD; Butzow, R; Campbell, IG; Chang-Claude, J; Chen, K; Cook, LS; Cramer, DW; deFazio, A; Dennis, J; Doherty, JA; Dörk, T; Eccles, DM; Edwards, DV; Fasching, PA; Fortner, RT; Gayther, SA; Giles, GG; Glasspool, RM; Goode, EL; Goodman, MT; Gronwald, J; Harris, HR; Heitz, F; Hildebrandt, MA; Høgdall, E; Høgdall, CK; Huntsman, DG; Kar, SP; Karlan, BY; Kelemen, LE; Kiemeney, LA; Kjaer, SK; Koushik, A; Lambrechts, D; Le, ND; Levine, DA; Massuger, LF; Matsuo, K; May, T; McNeish, IA; Menon, U; Modugno, F; Monteiro, AN; Moorman, PG; Moysich, KB; Ness, RB; Nevanlinna, H; Olsson, H; Onland-Moret, NC; Park, SK; Paul, J; Pearce, CL; Pejovic, T; Phelan, CM; Pike, MC; Ramus, SJ; Riboli, E; Rodriguez-Antona, C; Romieu, I; Sandler, DP; Schildkraut, JM; Setiawan, VW; Shan, K; Siddiqui, N; Sieh, W; Stampfer, MJ; Sutphen, R; Swerdlow, AJ; Szafron, LM; Teo, SH; Tworoger, SS; Tyrer, JP; Webb, PM; Wentzensen, N; White, E; Willett, WC; Wolk, A; Woo, YL; Wu, AH; Yan, L; Yannoukakos, D; Chenevix-Trench, G; Sellers, TA; Pharoah, PDP; Zheng, W; Long, J (2019-02-01)
    : DNA methylation is instrumental for gene regulation. Global changes in the epigenetic landscape have been recognized as a hallmark of cancer. However, the role of DNA methylation in epithelial ovarian cancer (EOC) remains ...
  • Exposure to loud noise and risk of vestibular schwannoma: results from the INTERPHONE international case‒control study. 

    Deltour, I; Schlehofer, B; Massardier-Pilonchéry, A; Schlaefer, K; Armstrong, B; Giles, GG; Siemiatycki, J; Parent, M-E; Krewski, D; McBride, M; Johansen, C; Auvinen, A; Salminen, T; Hours, M; Montestrucq, L; Blettner, M; Berg-Beckhoff, G; Sadetzki, S; Chetrit, A; Lagorio, S; Iavarone, I; Yamaguchi, N; Takebayashi, T; Woodward, A; Cook, A; Tynes, T; Klaeboe, L; Maria Feychting, MF; Lönn, S; Fleming, S; Swerdlow, AJ; Schoemaker, MJ; Moissonnier, M; Kesminiene, A; Cardis, E; Schüz, J; INTERPHONE Study Group (2018-11-05)
    Objective Studies of loud noise exposure and vestibular schwannomas (VS) have shown conflicting results. The population-based INTERPHONE case‒control study was conducted in 13 countries during 2000-2004. In this paper, we ...
  • Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study. 

    Rambau, PF; Vierkant, RA; Intermaggio, MP; Kelemen, LE; Goodman, MT; Herpel, E; Pharoah, PD; Kommoss, S; Jimenez-Linan, M; Karlan, BY; Gentry-Maharaj, A; Menon, U; Polo, SH; Candido Dos Reis, FJ; Doherty, JA; Gayther, SA; Sharma, R; Larson, MC; Harnett, PR; Hatfield, E; de Andrade, JM; Nelson, GS; Steed, H; Schildkraut, JM; Carney, ME; Høgdall, E; Whittemore, AS; Widschwendter, M; Kennedy, CJ; Wang, F; Wang, Q; Wang, C; Armasu, SM; Daley, F; Coulson, P; Jones, ME; Anglesio, MS; Chow, C; de Fazio, A; García-Closas, M; Brucker, SY; Cybulski, C; Harris, HR; Hartkopf, AD; Huzarski, T; Jensen, A; Lubiński, J; Oszurek, O; Benitez, J; Mina, F; Staebler, A; Taran, FA; Pasternak, J; Talhouk, A; Rossing, MA; Hendley, J; AOCS Group; Edwards, RP; Fereday, S; Modugno, F; Ness, RB; Sieh, W; El-Bahrawy, MA; Winham, SJ; Lester, J; Kjaer, SK; Gronwald, J; Sinn, P; Fasching, PA; Chang-Claude, J; Moysich, KB; Bowtell, DD; Hernandez, BY; Luk, H; Behrens, S; Shah, M; Jung, A; Ghatage, P; Alsop, J; Alsop, K; García-Donas, J; Thompson, PJ; Swerdlow, AJ; Karpinskyj, C; Cazorla-Jiménez, A; García, MJ; Deen, S; Wilkens, LR; Palacios, J; Berchuck, A; Koziak, JM; Brenton, JD; Cook, LS; Goode, EL; Huntsman, DG; Ramus, SJ; Köbel, M (2018-10)
    We aimed to validate the prognostic association of p16 expression in ovarian high-grade serous carcinomas (HGSC) and to explore it in other ovarian carcinoma histotypes. p16 protein expression was assessed by clinical-grade ...
  • Risks of ovarian, breast, and corpus uteri cancer in women treated with assisted reproductive technology in Great Britain, 1991-2010: data linkage study including 2.2 million person years of observation. 

    Williams, CL; Jones, ME; Swerdlow, AJ; Botting, BJ; Davies, MC; Jacobs, I; Bunch, KJ; Murphy, MFG; Sutcliffe, AG (2018-07-11)
    OBJECTIVE: To investigate the risks of ovarian, breast, and corpus uteri cancer in women who have had assisted reproduction. DESIGN: Large, population based, data linkage cohort study. SETTING AND PARTICIPANTS: All women ...

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