Browsing Breast Cancer Research by author "Yeung, Chit Sum Jason"
Now showing items 1-2 of 2
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Longitudinal profiling identifies co-occurring BRCA1/2 reversions, TP53BP1, RIF1 and PAXIP1 mutations in PARP inhibitor-resistant advanced breast cancer.
Harvey-Jones, E; Raghunandan, M; Robbez-Masson, L; Magraner-Pardo, L; Alaguthurai, T; et al. (ELSEVIER, 2024-01-19)BACKGROUND: Resistance to therapies that target homologous recombination deficiency (HRD) in breast cancer limits their overall effectiveness. Multiple, preclinically validated, mechanisms of resistance have been proposed, ... -
Next-Generation Sequencing and Image-Guided Tissue Sampling: A Primer for Interventional Radiologists.
Yeung, J; Fotiadis, N; Diamantopoulos, A; Tutt, A; Roxanis, I; et al. (Elsevier BV, 2023-03-01)The discovery of increasing numbers of actionable molecular and gene targets for cancer treatment has driven the demand for tissue sampling for next-generation sequencing (NGS). Requirements for sequencing can be very ...