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dc.contributor.authorBedford, JL
dc.contributor.authorThomas, MDR
dc.contributor.authorSmyth, G
dc.date.accessioned2018-07-23T15:11:37Z
dc.date.issued2013-05-06
dc.identifier.citationJournal of applied clinical medical physics, 2013, 14 (2), pp. 4136 - ?
dc.identifier.issn1526-9914
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2121
dc.identifier.eissn1526-9914
dc.identifier.doi10.1120/jacmp.v14i2.4136
dc.description.abstractThe Agility multileaf collimator (Elekta AB, Stockholm, Sweden) has 160 leaves of projected width 0.5 cm at the isocenter, with maximum leaf speed 3.5 cms-1. These characteristics promise to facilitate fast and accurate delivery of radiotherapy, particularly volumetric-modulated arc therapy (VMAT). The aim of this study is therefore to create a beam model for the Pinnacle3 treatment planning system (Philips Radiation Oncology Systems, Fitchburg, WI), and to use this beam model to explore the performance of the Agility MLC in delivery of VMAT. A 6 MV beam model was created and verified by measuring doses under irregularly shaped fields. VMAT treatment plans for five typical head-and-neck patients were created using the beam model and delivered using both binned and continuously variable dose rate (CVDR). Results were compared with those for an MLCi unit without CVDR. The beam model has similar parameters to those of an MLCi model, with interleaf leakage of only 0.2%. The verification of irregular fields shows a mean agreement between measured and planned dose of 1.3% (planned dose higher). The Agility VMAT head-and-neck plans show equivalent plan quality and delivery accuracy to those for an MLCi unit, with 95% of verification measurements within 3% and 3 mm of planned dose. Mean delivery time is 133 s with the Agility head and CVDR, 171 s without CVDR, and 282 s with an MLCi unit. Pinnacle3 has therefore been shown to model the Agility MLC accurately, and to provide accurate VMAT treatment plans which can be delivered significantly faster with Agility than with an MLCi.
dc.formatElectronic
dc.format.extent4136 - ?
dc.languageeng
dc.language.isoeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectHumans
dc.subjectHead and Neck Neoplasms
dc.subjectRadiotherapy Dosage
dc.subjectRadiotherapy Planning, Computer-Assisted
dc.subjectSensitivity and Specificity
dc.subjectReproducibility of Results
dc.subjectEquipment Design
dc.subjectEquipment Failure Analysis
dc.subjectRadiometry
dc.subjectRadiotherapy, Intensity-Modulated
dc.titleBeam modeling and VMAT performance with the Agility 160-leaf multileaf collimator.
dc.typeJournal Article
dcterms.dateAccepted2012-12-10
rioxxterms.versionofrecord10.1120/jacmp.v14i2.4136
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2013-05-06
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfJournal of applied clinical medical physics
pubs.issue2
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radiotherapy treatment planning
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radiotherapy treatment planning/Radiotherapy treatment planning (hon.)
pubs.organisational-group/ICR/Primary Group/Royal Marsden Clinical Units
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radiotherapy treatment planning
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radiotherapy treatment planning/Radiotherapy treatment planning (hon.)
pubs.organisational-group/ICR/Primary Group/Royal Marsden Clinical Units
pubs.publication-statusPublished
pubs.volume14
pubs.embargo.termsNot known
icr.researchteamRadiotherapy treatment planningen_US
dc.contributor.icrauthorBedford, James L
dc.contributor.icrauthorSmyth, Gregory


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