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dc.contributor.authorGreaves, M
dc.contributor.authorHughes, W
dc.date.accessioned2018-11-19T12:47:36Z
dc.date.issued2018-01-01
dc.identifier.citationEvolution, medicine, and public health, 2018, 2018 (1), pp. 106 - 115
dc.identifier.issn2050-6201
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2947
dc.identifier.eissn2050-6201
dc.identifier.doi10.1093/emph/eoy011
dc.description.abstractCancer cells have a parasitic propensity in the primary host but their capacity to transit between individuals is severely restrained by two factors: a lack of a route for viable cell transfer and immune recognition in allogeneic, secondary recipients. Several examples of transmissible animal cancers are now recognised. In humans, the only natural route for transmission is via the haemochorial placenta which is permissive for cell traffic. There are three special examples of this occurring in utero: maternal to foetus, intraplacental twin to twin leukaemias and choriocarcinoma-extra-embryonic cells to mother. We discuss the rare circumstances under which such transmission occurs.
dc.formatElectronic-eCollection
dc.format.extent106 - 115
dc.languageeng
dc.language.isoeng
dc.publisherOXFORD UNIV PRESS
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleCancer cell transmission via the placenta.
dc.typeJournal Article
dcterms.dateAccepted2018-04-02
rioxxterms.versionofrecord10.1093/emph/eoy011
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2018-01
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfEvolution, medicine, and public health
pubs.issue1
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Biology of Childhood Leukaemia
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Biology of Childhood Leukaemia
pubs.publication-statusPublished
pubs.volume2018
pubs.embargo.termsNot known
icr.researchteamBiology of Childhood Leukaemia
dc.contributor.icrauthorGreaves, Melvyn


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