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dc.contributor.authorGreaves, Men_US
dc.contributor.authorHughes, Wen_US
dc.coverage.spatialEnglanden_US
dc.date.accessioned2018-11-19T12:47:36Z
dc.date.issued2018en_US
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/29765597en_US
dc.identifiereoy011en_US
dc.identifier.citationEvol Med Public Health, 2018, 2018 (1), pp. 106 - 115en_US
dc.identifier.issn2050-6201en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/2947
dc.identifier.doi10.1093/emph/eoy011en_US
dc.description.abstractCancer cells have a parasitic propensity in the primary host but their capacity to transit between individuals is severely restrained by two factors: a lack of a route for viable cell transfer and immune recognition in allogeneic, secondary recipients. Several examples of transmissible animal cancers are now recognised. In humans, the only natural route for transmission is via the haemochorial placenta which is permissive for cell traffic. There are three special examples of this occurring in utero: maternal to foetus, intraplacental twin to twin leukaemias and choriocarcinoma-extra-embryonic cells to mother. We discuss the rare circumstances under which such transmission occurs.en_US
dc.format.extent106 - 115en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectcancer clonal markersen_US
dc.subjectchoriocarcinomaen_US
dc.subjecthaemochorial placentaen_US
dc.subjectimmune evasionen_US
dc.subjectplacental anastomosesen_US
dc.titleCancer cell transmission via the placenta.en_US
dc.typeJournal Article
dcterms.dateAccepted2018-04-02en_US
rioxxterms.versionofrecord10.1093/emph/eoy011en_US
rioxxterms.licenseref.startdate2018en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfEvol Med Public Healthen_US
pubs.issue1en_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Biology of Childhood Leukaemia
pubs.publication-statusPublished onlineen_US
pubs.volume2018en_US
pubs.embargo.termsNot knownen_US
icr.researchteamBiology of Childhood Leukaemiaen_US
dc.contributor.icrauthorGreaves, Melvynen_US


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/