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dc.contributor.authorKaalep, Aen_US
dc.contributor.authorSera, Ten_US
dc.contributor.authorOyen, Wen_US
dc.contributor.authorKrause, BJen_US
dc.contributor.authorChiti, Aen_US
dc.contributor.authorLiu, Yen_US
dc.contributor.authorBoellaard, Ren_US
dc.coverage.spatialGermanyen_US
dc.date.accessioned2018-02-14T15:09:06Z
dc.date.accessioned2019-02-25T16:21:08Z
dc.date.issued2018-03en_US
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/29192365en_US
dc.identifier10.1007/s00259-017-3853-7en_US
dc.identifier.citationEur J Nucl Med Mol Imaging, 2018, 45 (3), pp. 412 - 422en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3089
dc.identifier.eissn1619-7089en_US
dc.identifier.doi10.1007/s00259-017-3853-7en_US
dc.description.abstractPURPOSE: From 2010 until July 2016, the EANM Research Ltd. (EARL) FDG-PET/CT accreditation program has collected over 2500 phantom datasets from approximately 200 systems and 150 imaging sites worldwide. The objective of this study is to report the findings and impact of the accreditation program on the participating PET/CT systems. METHODS: To obtain and maintain EARL accredited status, sites were required to complete and submit two phantom scans - calibration quality control (CalQC), using a uniform cylindrical phantom and image quality control (IQQC), using a NEMA NU2-2007 body phantom. Average volumetric SUV bias and SUV recovery coefficients (RC) were calculated and the data evaluated on the basis of quality control (QC) type, approval status, PET/CT system manufacturer and submission order. RESULTS: SUV bias in 5% (n = 96) of all CalQC submissions (n = 1816) exceeded 10%. After corrective actions following EARL feedback, sites achieved 100% compliance within EARL specifications. 30% (n = 1381) of SUVmean and 23% (n = 1095) of SUVmax sphere recoveries from IQQC submissions failed to meet EARL accreditation criteria while after accreditation, failure rate decreased to 12% (n = 360) and 9% (n = 254), respectively. Most systems demonstrated longitudinal SUV bias reproducibility within ±5%, while RC values remained stable and generally within ±10% for the four largest and ±20% for the two smallest spheres. CONCLUSIONS: Regardless of manufacturer or model, all investigated systems are able to comply with the EARL specifications. Within the EARL accreditation program, gross PET/CT calibration errors are successfully identified and longitudinal variability in PET/CT performances reduced. The program demonstrates that a harmonising accreditation procedure is feasible and achievable.en_US
dc.format.extent412 - 422en_US
dc.languageengen_US
dc.language.isoengen_US
dc.relation.replaceshttps://repository.icr.ac.uk/handle/internal/1078
dc.relation.replacesinternal/1078
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectEARL accreditationen_US
dc.subjectHarmonisationen_US
dc.subjectPET/CTen_US
dc.subjectPerformanceen_US
dc.subjectQuantificationen_US
dc.subjectAccreditationen_US
dc.subjectCalibrationen_US
dc.subjectFluorodeoxyglucose F18en_US
dc.subjectNuclear Medicineen_US
dc.subjectPhantoms, Imagingen_US
dc.subjectPositron Emission Tomography Computed Tomographyen_US
dc.subjectSocieties, Medicalen_US
dc.titleEANM/EARL FDG-PET/CT accreditation - summary results from the first 200 accredited imaging systems.en_US
dc.typeJournal Article
dcterms.dateAccepted2017-10-05en_US
rioxxterms.versionofrecord10.1007/s00259-017-3853-7en_US
rioxxterms.licenseref.startdate2018-03en_US
rioxxterms.typeJournal Article/Reviewen_US
dc.relation.isPartOfEur J Nucl Med Mol Imagingen_US
pubs.issue3en_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Molecular Imaging
pubs.organisational-group/ICR/Primary Group/Royal Marsden Clinical Units
pubs.publication-statusPublisheden_US
pubs.volume45en_US
pubs.embargo.termsNot knownen_US
icr.researchteamTranslational Molecular Imagingen_US
dc.contributor.icrauthorOyen, Willemen_US
dc.contributor.icrauthorMarsden,en_US


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