Circulating cell-free DNA: Translating prostate cancer genomics into clinical care.
View/ Open
Date
2020-04-01ICR Author
Author
Gasi Tandefelt, D
de Bono, J
Type
Journal Article
Metadata
Show full item recordAbstract
Only in the past decade tremendous advances have been made in understanding prostate cancer genomics and consequently in applying new treatment strategies. As options regarding treatments are increasing so are the challenges in selecting the right treatment option for each patient and not the least, understanding the optimal time-point and sequence of applying available treatments. Critically, without reliable methods that enable sequential monitoring of evolving genotypes in individual patients, we will never reach effective personalised driven treatment approaches. This review focuses on the clinical implications of prostate cancer genomics and the potential of cfDNA in facilitating treatment management.
Collections
Research team
Prostate Cancer Targeted Therapy Group
Language
eng
Date accepted
2019-12-13
License start date
2020-04
Citation
Molecular aspects of medicine, 2020, 72 pp. 100837 - ?
Publisher
ELSEVIER