dc.contributor.author | Eccles, CL | |
dc.contributor.author | Adair Smith, G | |
dc.contributor.author | Bower, L | |
dc.contributor.author | Hafeez, S | |
dc.contributor.author | Herbert, T | |
dc.contributor.author | Hunt, A | |
dc.contributor.author | McNair, HA | |
dc.contributor.author | Ofuya, M | |
dc.contributor.author | Oelfke, U | |
dc.contributor.author | Nill, S | |
dc.contributor.author | Huddart, RA | |
dc.contributor.author | PRIMER TMG, | |
dc.date.accessioned | 2020-03-09T09:37:11Z | |
dc.date.issued | 2019-12-16 | |
dc.identifier.citation | Technical innovations & patient support in radiation oncology, 2019, 12 pp. 56 - 63 | |
dc.identifier.issn | 2405-6324 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/3539 | |
dc.identifier.eissn | 2405-6324 | |
dc.identifier.doi | 10.1016/j.tipsro.2019.11.004 | |
dc.description.abstract | OBJECTIVES: To systematically identify the preferred magnetic resonance imaging (MRI) sequences following volunteer imaging on a 1.5 Tesla (T) MR-Linear Accelerator (MR Linac) for future protocol development. METHODS: Non-patient volunteers were recruited to a Research and Ethics committee approved prospective MR-only imaging study on a 1.5T MR Linac system. Volunteers attended 1-3 imaging sessions that included a combination of mDixon, T1w, T2w sequences using 2-dimensional (2D) and 3-dimensional (3D) acquisitions. Each sequence was acquired over 2-7 minutes and reviewed by a panel of 3 observers to evaluate image quality using a visual grading analysis based on a 4-point Likert scale. Sequences were acquired and modified iteratively until deemed fit for purpose (online image matching or re-planning) and all observers agreed they were suitable in 3 volunteers. RESULTS: 26 volunteers underwent 31 imaging sessions of six general anatomical regions. Images were acquired in one or two of six general anatomical regions: male pelvis (n = 9), female pelvis (n = 4), chestwall/breast (n = 5), lung/oesophagus (n = 5), abdomen (n = 3) and head and neck (n = 5). Images were acquired using a pre-defined exam-card that on average, included six sequences (range 2-10), with a maximum scan time of approximately one hour. The majority of observers preferred T2-weighted sequences. The thorax teams were the only groups to prefer T1-weighted imaging. CONCLUSIONS: An iterative process identified sequence agreement in all anatomical regions. These sequences will now be evaluated in patient volunteers. ADVANCES IN KNOWLEDGE: This manuscript is the first publication sharing the results of the first systematic selection of MRI sequences for use in on-board MRI-guided radiotherapy by end-users (therapeutic radiographers and clinical oncologists) in healthy volunteers. | |
dc.format | Electronic-eCollection | |
dc.format.extent | 56 - 63 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | Elsevier BV | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.subject | PRIMER TMG | |
dc.title | Magnetic resonance imaging sequence evaluation of an MR Linac system; early clinical experience. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2019-11-11 | |
rioxxterms.versionofrecord | 10.1016/j.tipsro.2019.11.004 | |
rioxxterms.licenseref.uri | https://creativecommons.org/licenses/by-nc-nd/4.0 | |
rioxxterms.licenseref.startdate | 2019-12-16 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | Technical innovations & patient support in radiation oncology | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Clinical Academic Radiotherapy (Huddart) | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radiotherapy Physics Modelling | |
pubs.organisational-group | /ICR/Primary Group/Royal Marsden Clinical Units | |
pubs.publication-status | Published | |
pubs.volume | 12 | |
pubs.embargo.terms | Not known | |
icr.researchteam | Clinical Academic Radiotherapy (Huddart) | |
icr.researchteam | Radiotherapy Physics Modelling | |
dc.contributor.icrauthor | Hafeez, Shaista | |
dc.contributor.icrauthor | Nill, Simeon | |
dc.contributor.icrauthor | Huddart, Robert | |