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dc.contributor.authorRees, G
dc.contributor.authorSalto-Tellez, M
dc.contributor.authorLee, JL
dc.contributor.authorOien, K
dc.contributor.authorVerrill, C
dc.contributor.authorFreeman, A
dc.contributor.authorMirabile, I
dc.contributor.authorWest, NP
dc.contributor.authorNational Cancer Research Institute (NCRI) Cellular-Molecular Pathology (CM-Path) clinical trials working group
dc.date.accessioned2020-06-09T12:02:59Z
dc.date.issued2019-04
dc.identifier.citationThe journal of pathology. Clinical research, 2019, 5 (2), pp. 100 - 107
dc.identifier.issn2056-4538
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3717
dc.identifier.eissn2056-4538
dc.identifier.doi10.1002/cjp2.124
dc.description.abstractClinical trials rely on multidisciplinary teams for successful delivery. Pathologists should be involved in clinical trial design from the outset to ensure that protocols are optimised to deliver maximum data collection and translational research opportunities. Clinical trials must be performed according to the principles of Good Clinical Practice (GCP) and the trial sponsor has an obligation to ensure that all of the personnel involved in the trial have undergone training relevant to their role. Pathologists who are involved in the delivery of clinical trials are often required to undergo formal GCP training and may additionally undergo Good Clinical Laboratory Practice training if they are involved in the laboratory analysis of trials samples. Further training can be provided via trial-specific investigator meetings, which may be either multidisciplinary or discipline-specific events. Pathologists should also ensure that they undertake External Quality Assurance schemes relevant to the area of diagnostic practice required in the trial. The level of engagement of pathologists in academia and clinical trials research has declined in the United Kingdom over recent years. This paper recommends the optimal training and accreditation for pathologists undertaking clinical trials activities with the aim of facilitating increased engagement. Clinical trials training should ideally be provided to all pathologists through centrally organised educational events, with additional training provided to pathologists in training through local postgraduate teaching. Pathologists in training should also be strongly encouraged to undertake GCP training. It is hoped that these recommendations will increase the number of pathologists who take part in clinical trials research in order to ensure a high level and standard of data collection and to maximise the translational research opportunities.
dc.formatPrint-Electronic
dc.format.extent100 - 107
dc.languageeng
dc.language.isoeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectNational Cancer Research Institute (NCRI) Cellular-Molecular Pathology (CM-Path) clinical trials working group
dc.subjectHumans
dc.subjectReproducibility of Results
dc.subjectPathology, Clinical
dc.subjectResearch Personnel
dc.subjectLaboratories
dc.subjectAccreditation
dc.subjectUnited Kingdom
dc.subjectPathologists
dc.titleTraining and accreditation standards for pathologists undertaking clinical trial work.
dc.typeJournal Article
dcterms.dateAccepted2019-01-20
rioxxterms.versionofrecord10.1002/cjp2.124
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2019-04
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfThe journal of pathology. Clinical research
pubs.issue2
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Genomic Analysis – Clinical Trials
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Integrated Pathology
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Genomic Analysis – Clinical Trials
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Molecular Pathology/Integrated Pathology
pubs.publication-statusPublished
pubs.volume5
pubs.embargo.termsNot known
icr.researchteamGenomic Analysis – Clinical Trialsen_US
icr.researchteamIntegrated Pathologyen_US
dc.contributor.icrauthorSalto-Tellez, Manuelen
dc.contributor.icrauthorCheang, Chonen


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