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Fragment growing to retain or alter the selectivity of anchored kinase hinge-binding fragments

dc.contributor.authorAllen, CE
dc.contributor.authorWelford, AJ
dc.contributor.authorMatthews, TP
dc.contributor.authorCaldwell, JJ
dc.contributor.authorCollins, I
dc.date.accessioned2020-08-17T15:22:26Z
dc.date.issued2014-01-01
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330797000009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=d4b848928d1c3e5c86d298abb68475f9
dc.identifier.citationMEDCHEMCOMM, 2014, 5 (2), pp. 180 - 185 (6)
dc.identifier.issn2040-2503
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3976
dc.identifier.eissn2040-2511
dc.identifier.doi10.1039/c3md00308f
dc.description.abstract<p>The selectivity patterns of kinase hinge-binding fragments can be retained during fragment growing, suggesting a new way to control poly-pharmacology.</p>
dc.format.extent180 - 185 (6)
dc.languageeng
dc.language.isoeng
dc.publisherROYAL SOC CHEMISTRY
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectBiochemistry & Molecular Biology
dc.subjectChemistry, Medicinal
dc.subjectPharmacology & Pharmacy
dc.subjectINHIBITORS
dc.subjectDISCOVERY
dc.subjectCANCER
dc.subjectIDENTIFICATION
dc.subjectEVOLUTION
dc.subjectTYROSINE
dc.titleFragment growing to retain or alter the selectivity of anchored kinase hinge-binding fragments
dc.typeJournal Article
rioxxterms.versionofrecord10.1039/c3md00308f
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2014-01-01
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfMEDCHEMCOMM
pubs.issue2
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Medicinal Chemistry 2
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Medicinal Chemistry 2
pubs.publication-statusPublished
pubs.volume5
pubs.embargo.termsNot known
icr.researchteamMedicinal Chemistry 2
dc.contributor.icrauthorMatthews, Thomas
dc.contributor.icrauthorCaldwell, John
dc.contributor.icrauthorCollins, Ian


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