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dc.contributor.authorNewton, G
dc.contributor.authorStewart, M
dc.contributor.otherJenkins, K
dc.contributor.otherPerrior, T
dc.contributor.otherNegoita-Giras, G
dc.contributor.otherCrosby, S
dc.contributor.otherHopkins, A
dc.coverage.spatialInternational
dc.date.accessioned2020-08-19T09:51:02Z
dc.date.issued2014-08-28
dc.identifierGB2014050521W
dc.identifierWO2014128486 (and associated family)
dc.identifier.citation2014
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3986
dc.description.abstractCompounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases &Igr;&Kgr;&Kgr;&egr; and/or TBK-1 in which one of V and W is N, and the other of V and W is C-H; and R1, R2, R3 and R4 are as defined in the specification. The invention also provides uses of the compounds and compositions containing them.
dc.languageeng
dc.language.isoeng
dc.subjectKinase
dc.subjectInflammation
dc.subjectCancer
dc.titlePYRIMIDINE COMPOUNDS USEFUL IN THE TREATMENT OF DISEASES MEDIATED BY IKKE AND/OR TBK1 MECHANISMS
dc.typePatent
rioxxterms.licenseref.startdate2014-08-28
rioxxterms.typeOther
pubs.filed-date2014-02-21
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Medicinal Chemistry 3
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Medicinal Chemistry 3
pubs.patent-statusGranted in multiple territories
pubs.start-date2016-08-03
pubs.embargo.termsNot known
icr.researchteamMedicinal Chemistry 3en_US
dc.contributor.icrauthorNewton, Garyen


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