PYRIMIDINE COMPOUNDS USEFUL IN THE TREATMENT OF DISEASES MEDIATED BY IKKE AND/OR TBK1 MECHANISMS
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Date
2014-08-28ICR Author
Author
Newton, G
Stewart, M
Jenkins, K
Perrior, T
Negoita-Giras, G
Crosby, S
Hopkins, A
Type
Patent
Metadata
Show full item recordAbstract
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases &Igr;&Kgr;&Kgr;&egr; and/or TBK-1 in which one of V and W is N, and the other of V and W is C-H; and R1, R2, R3 and R4 are as defined in the specification. The invention also provides uses of the compounds and compositions containing them.
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Subject
Kinase
Inflammation
Cancer
Research team
Medicinal Chemistry 3
Language
eng
License start date
2014-08-28
Citation
2014