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PYRIMIDINE COMPOUNDS USEFUL IN THE TREATMENT OF DISEASES MEDIATED BY IKKE AND/OR TBK1 MECHANISMS

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Date
2014-08-28
ICR Author
Newton, Gary
Author
Newton, G
Stewart, M
Jenkins, K
Perrior, T
Negoita-Giras, G
Crosby, S
Hopkins, A
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Type
Patent
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Abstract
Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases &Igr;&Kgr;&Kgr;&egr; and/or TBK-1 in which one of V and W is N, and the other of V and W is C-H; and R1, R2, R3 and R4 are as defined in the specification. The invention also provides uses of the compounds and compositions containing them.
URI
https://repository.icr.ac.uk/handle/internal/3986
Collections
  • Cancer Therapeutics
Subject
Kinase
Inflammation
Cancer
Research team
Medicinal Chemistry 3
Language
eng
License start date
2014-08-28
Citation
2014

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