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dc.contributor.authorGalluzzi, L
dc.contributor.authorVitale, I
dc.contributor.authorWarren, S
dc.contributor.authorAdjemian, S
dc.contributor.authorAgostinis, P
dc.contributor.authorMartinez, AB
dc.contributor.authorChan, TA
dc.contributor.authorCoukos, G
dc.contributor.authorDemaria, S
dc.contributor.authorDeutsch, E
dc.contributor.authorDraganov, D
dc.contributor.authorEdelson, RL
dc.contributor.authorFormenti, SC
dc.contributor.authorFucikova, J
dc.contributor.authorGabriele, L
dc.contributor.authorGaipl, US
dc.contributor.authorGameiro, SR
dc.contributor.authorGarg, AD
dc.contributor.authorGolden, E
dc.contributor.authorHan, J
dc.contributor.authorHarrington, KJ
dc.contributor.authorHemminki, A
dc.contributor.authorHodge, JW
dc.contributor.authorHossain, DMS
dc.contributor.authorIllidge, T
dc.contributor.authorKarin, M
dc.contributor.authorKaufman, HL
dc.contributor.authorKepp, O
dc.contributor.authorKroemer, G
dc.contributor.authorLasarte, JJ
dc.contributor.authorLoi, S
dc.contributor.authorLotze, MT
dc.contributor.authorManic, G
dc.contributor.authorMerghoub, T
dc.contributor.authorMelcher, AA
dc.contributor.authorMossman, KL
dc.contributor.authorProsper, F
dc.contributor.authorRekdal, Ø
dc.contributor.authorRescigno, M
dc.contributor.authorRiganti, C
dc.contributor.authorSistigu, A
dc.contributor.authorSmyth, MJ
dc.contributor.authorSpisek, R
dc.contributor.authorStagg, J
dc.contributor.authorStrauss, BE
dc.contributor.authorTang, D
dc.contributor.authorTatsuno, K
dc.contributor.authorvan Gool, SW
dc.contributor.authorVandenabeele, P
dc.contributor.authorYamazaki, T
dc.contributor.authorZamarin, D
dc.contributor.authorZitvogel, L
dc.contributor.authorCesano, A
dc.contributor.authorMarincola, FM
dc.date.accessioned2020-08-24T09:17:19Z
dc.date.issued2020-03
dc.identifier.citationJournal for immunotherapy of cancer, 2020, 8 (1)
dc.identifier.issn2051-1426
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/3996
dc.identifier.eissn2051-1426
dc.identifier.doi10.1136/jitc-2019-000337
dc.description.abstractCells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenvironmental features determine the propensity of RCD to drive adaptive immunity. Here, we provide an updated operational definition of immunogenic cell death (ICD), discuss the key factors that dictate the ability of dying cells to drive an adaptive immune response, summarize experimental assays that are currently available for the assessment of ICD in vitro and in vivo, and formulate guidelines for their interpretation.
dc.formatPrint
dc.languageeng
dc.language.isoeng
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleConsensus guidelines for the definition, detection and interpretation of immunogenic cell death.
dc.typeJournal Article
dcterms.dateAccepted2020-01-13
rioxxterms.versionofrecord10.1136/jitc-2019-000337
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2020-03
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfJournal for immunotherapy of cancer
pubs.issue1
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Immunotherapy
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Immunotherapy/Translational Immunotherapy (TL)
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Immunotherapy
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Translational Immunotherapy/Translational Immunotherapy (TL)
pubs.publication-statusPublished
pubs.volume8
pubs.embargo.termsNot known
icr.researchteamTranslational Immunotherapyen_US
dc.contributor.icrauthorMelcher, Alanen


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