Now showing items 1-4 of 4

    • Characterisation of the immune-related transcriptome in resected biliary tract cancers. 

      Ghidini, M; Cascione, L; Carotenuto, P; Lampis, A; Trevisani, F; Previdi, MC; Hahne, JC; Said-Huntingford, I; Raj, M; Zerbi, A; Mescoli, C; Cillo, U; Rugge, M; Roncalli, M; Torzilli, G; Rimassa, L; Santoro, A; Valeri, N; Fassan, M; Braconi, C (2017-11)
      Although biliary tract cancers (BTCs) are known to have an inflammatory component, a detailed characterisation of immune-related transcripts has never been performed. In these studies, nCounter PanCancer Immune Profiling ...
    • MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma. 

      Lampis, A; Carotenuto, P; Vlachogiannis, G; Cascione, L; Hedayat, S; Burke, R; Clarke, P; Bosma, E; Simbolo, M; Scarpa, A; Yu, S; Cole, R; Smyth, E; Mateos, JF; Begum, R; Hezelova, B; Eltahir, Z; Wotherspoon, A; Fotiadis, N; Bali, MA; Nepal, C; Khan, K; Stubbs, M; Hahne, JC; Gasparini, P; Guzzardo, V; Croce, CM; Eccles, S; Fassan, M; Cunningham, D; Andersen, JB; Workman, P; Valeri, N; Braconi, C (2018-03)
      BACKGROUND & AIMS: Cholangiocarcinomas (CCA) are resistant to chemotherapy, so new therapeutic agents are needed. We performed a screen to identify small-molecule compounds that are active against CCAs. Levels of microRNA ...
    • Noncoding RNAs as novel biomarkers in pancreatic cancer: what do we know? 

      Previdi, MC; Carotenuto, P; Zito, D; Pandolfo, R; Braconi, C (2017-02)
      Pancreatic cancer is an aggressive cancer of the digestive system, which is becoming a serious health problem worldwide. Overall survival for patients with pancreatic cancer is poor, mainly due to a lack of biomarkers to ...
    • Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers. 

      Carotenuto, P; Fassan, M; Pandolfo, R; Lampis, A; Vicentini, C; Cascione, L; Paulus-Hock, V; Boulter, L; Guest, R; Quagliata, L; Hahne, JC; Ridgway, R; Jamieson, T; Athineos, D; Veronese, A; Visone, R; Murgia, C; Ferrari, G; Guzzardo, V; Evans, TR; MacLeod, M; Feng, GJ; Dale, T; Negrini, M; Forbes, SJ; Terracciano, L; Scarpa, A; Patel, T; Valeri, N; Workman, P; Sansom, O; Braconi, C (2016-09-12)
      Transcribed-ultraconserved regions (T-UCR) are long non-coding RNAs which are conserved across species and are involved in carcinogenesis. We studied T-UCRs downstream of the Wnt/β-catenin pathway in liver cancer.Hypomorphic ...