Show simple item record

Unconventional role of RAC1 in MET-driven anchorage-independent tumor growth.

dc.contributor.authorHervieu, A
dc.contributor.authorKermorgant, S
dc.date.accessioned2020-11-03T15:51:33Z
dc.date.issued2020-08-18
dc.identifier.citationMolecular & cellular oncology, 2020, 7 (6), pp. 1803029 - ?
dc.identifier.issn2372-3556
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/4209
dc.identifier.eissn2372-3556
dc.identifier.doi10.1080/23723556.2020.1803029
dc.description.abstractWe reported that RAC1 is a master regulator of cell migration and anchorage-independent growth, downstream of the oncogenic Receptor Tyrosine Kinase (RTK) MET. RAC1 growth-promoting role is guanosine triphosphatase (GTPase)- and phosphatidylinositol 3-kinase (PI3K)-independent but promotes mammalian target of rapamycin (mTOR) signaling through triggering its plasma membrane localization.
dc.formatElectronic
dc.format.extent1803029 - ?
dc.languageeng
dc.language.isoeng
dc.publisherTAYLOR & FRANCIS INC
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.titleUnconventional role of RAC1 in MET-driven anchorage-independent tumor growth.
dc.typeJournal Article
rioxxterms.versionofrecord10.1080/23723556.2020.1803029
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.licenseref.startdate2020-08-18
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfMolecular & cellular oncology
pubs.issue6
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Signal Transduction & Molecular Pharmacology
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Cancer Therapeutics/Signal Transduction & Molecular Pharmacology
pubs.publication-statusPublished
pubs.volume7
pubs.embargo.termsNot known
icr.researchteamSignal Transduction & Molecular Pharmacology
dc.contributor.icrauthorHervieu Vilches, Alexia


Files in this item

Thumbnail
Name:
Unconventional role of RAC1 in ...
Size:
2.222Mb
Format:
PDF
Description:
Published version
View/Open

This item appears in the following collection(s)

Show simple item record

https://creativecommons.org/licenses/by/4.0
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0