LMO2 and IL2RG synergize in thymocytes to mimic the evolution of SCID-X1 gene therapy-associated T-cell leukaemia.

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Date

2016-09

ICR Author

Rabbitts, Terence

Author

Ruggero, K

Al-Assar, O

Chambers, JS

Codrington, R

Brend, T

Rabbitts, TH

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Type

Journal Article

Metadata

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URI

https://repository.icr.ac.uk/handle/internal/4266

DOI

https://doi.org/10.1038/leu.2016.116

Collections

• Cancer Therapeutics

Subject

Animals

Mice, Transgenic

Mice

Leukemia, T-Cell

Adaptor Proteins, Signal Transducing

Interleukin Receptor Common gamma Subunit

X-Linked Combined Immunodeficiency Diseases

LIM Domain Proteins

Thymocytes

Genetic Therapy

Research team

Chromosomal Translocations and Intracellular Antibody Therapeutics

Language

eng

License start date

2016-09

Citation

Leukemia, 2016, 30 (9), pp. 1959 - 1962