dc.contributor.author | Riexinger, A | |
dc.contributor.author | Martin, J | |
dc.contributor.author | Wetscherek, A | |
dc.contributor.author | Kuder, TA | |
dc.contributor.author | Uder, M | |
dc.contributor.author | Hensel, B | |
dc.contributor.author | Laun, FB | |
dc.date.accessioned | 2021-01-22T15:51:08Z | |
dc.date.issued | 2021-04-01 | |
dc.identifier.citation | Magnetic resonance in medicine, 2021, 85 (4), pp. 2095 - 2108 | |
dc.identifier.issn | 0740-3194 | |
dc.identifier.uri | https://repository.icr.ac.uk/handle/internal/4309 | |
dc.identifier.eissn | 1522-2594 | |
dc.identifier.doi | 10.1002/mrm.28582 | |
dc.description.abstract | PURPOSE: To find an optimized b-value distribution for reproducible triexponential intravoxel incoherent motion (IVIM) exams in the liver. METHODS: A numeric optimization of b-value distributions was performed using the triexponential IVIM equation and 27 different IVIM parameter sets. Starting with an initially optimized distribution of 6 b-values, the number of b-values was increased stepwise. Each new b-value was chosen from a set of 64 predefined b-values based on the computed summed relative mean error of the fitted triexponential IVIM parameters. This process was repeated for up to 100 b-values. In simulations and in vivo measurements, optimized b-value distributions were compared to 4 representative distributions found in literature. RESULTS: The first 16 optimized b-values were 0, 0.3, 0.3, 70, 200, 800, 70, 1, 3.5, 5, 70, 1.2, 6, 45, 1.5, and 60 in units of s/mm2 . Low b-values were much more frequent than high b-values. The optimized b-value distribution resulted in a higher fit stability compared to distributions used in literature in both, simulation and in vivo measurements. Using more than 6 b-values, ideally 16 or more, increased the fit stability considerably. CONCLUSION: Using optimized b-values, the fit uncertainty in triexponential IVIM can be largely reduced. Ideally, 16 or more b-values should be acquired. | |
dc.format | Print-Electronic | |
dc.format.extent | 2095 - 2108 | |
dc.language | eng | |
dc.language.iso | eng | |
dc.publisher | WILEY | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0 | |
dc.title | An optimized b-value distribution for triexponential intravoxel incoherent motion (IVIM) in the liver. | |
dc.type | Journal Article | |
dcterms.dateAccepted | 2020-10-13 | |
rioxxterms.versionofrecord | 10.1002/mrm.28582 | |
rioxxterms.licenseref.uri | https://creativecommons.org/licenses/by/4.0 | |
rioxxterms.licenseref.startdate | 2021-04 | |
rioxxterms.type | Journal Article/Review | |
dc.relation.isPartOf | Magnetic resonance in medicine | |
pubs.issue | 4 | |
pubs.notes | Not known | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radiotherapy Physics Modelling | |
pubs.organisational-group | /ICR | |
pubs.organisational-group | /ICR/Primary Group | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging | |
pubs.organisational-group | /ICR/Primary Group/ICR Divisions/Radiotherapy and Imaging/Radiotherapy Physics Modelling | |
pubs.publication-status | Accepted | |
pubs.volume | 85 | |
pubs.embargo.terms | Not known | |
icr.researchteam | Radiotherapy Physics Modelling | |
dc.contributor.icrauthor | Wetscherek, Andreas | |