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dc.contributor.authorTyler, J
dc.contributor.authorBernstein, D
dc.contributor.authorSeithel, M
dc.contributor.authorRooney, K
dc.contributor.authorPetkar, I
dc.contributor.authorMiles, E
dc.contributor.authorClark, CH
dc.contributor.authorHall, E
dc.contributor.authorNutting, C
dc.coverage.spatialNetherlandsen_US
dc.date.accessioned2021-11-23T14:14:35Z
dc.date.available2021-11-23T14:14:35Z
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/34754954en_US
dc.identifierS2405-6316(21)00058-0en_US
dc.identifier.citationPhys Imaging Radiat Oncol, 2021, 20 pp. 46 - 50en_US
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/4895
dc.identifier.eissn2405-6316en_US
dc.identifier.eissn2405-6316
dc.identifier.doi10.1016/j.phro.2021.10.003en_US
dc.identifier.doi10.1016/j.phro.2021.10.003
dc.description.abstractThis study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial. Protocol compliant plans were used for a single benchmark planning case. Larger margins were associated with higher doses to adjacent organs at risk, particularly the inferior pharyngeal constrictor muscle, but coincided with some improved low dose target coverage. A 3 mm margin is recommended for this technique if local practices allow.en_US
dc.format.extent46 - 50en_US
dc.languageengen_US
dc.language.isoengen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en_US
dc.subjectCERR, Computational Environment for Radiotherapy Researchen_US
dc.subjectDARS, dysphagia/aspiration related structuresen_US
dc.subjectDICOM, Digital Imaging and Communications in Medicineen_US
dc.subjectDO-IMRT, dysphagia optimised intensity modulated radiotherapyen_US
dc.subjectDysphagiaen_US
dc.subjectHead and neck canceren_US
dc.subjectICR-CTSU, Clinical Trials and Statistics Unit and the Institute of Cancer Researchen_US
dc.subjectIPCM, inferior pharyngeal constrictor muscleen_US
dc.subjectIntensity modulated radiotherapy (IMRT)en_US
dc.subjectNIHR, National Institute for Health Researchen_US
dc.subjectPAF, plan assessment formen_US
dc.subjectQuality assuranceen_US
dc.subjectRTQA, radiotherapy quality assuranceen_US
dc.subjectRTTQA, UK’s National Radiotherapy Trials Quality Assurance Groupen_US
dc.subjectRandomised controlled trialen_US
dc.subjectS-IMRT, standard intensity modulated radiotherapyen_US
dc.subjectSMPCM, superior and middle pharyngeal constrictor musclesen_US
dc.subjectTMG, Trial Management Groupen_US
dc.subjectVolumetric arc therapy (VMAT)en_US
dc.titleQuality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer.en_US
dc.typeJournal Article
dcterms.dateAccepted2021-10-10
rioxxterms.versionVoRen_US
rioxxterms.versionofrecord10.1016/j.phro.2021.10.003en_US
dc.relation.isPartOfPhys Imaging Radiat Oncolen_US
pubs.notesNot knownen_US
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Clinical Trials & Statistics Unit
pubs.publication-statusPublished onlineen_US
pubs.volume20en_US
pubs.embargo.termsNot knownen_US
icr.researchteamClinical Trials & Statistics Unit
dc.contributor.icrauthorHall, Emmaen_US


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Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/