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dc.contributor.authorTyler, J
dc.contributor.authorBernstein, D
dc.contributor.authorSeithel, M
dc.contributor.authorRooney, K
dc.contributor.authorPetkar, I
dc.contributor.authorMiles, E
dc.contributor.authorClark, CH
dc.contributor.authorHall, E
dc.contributor.authorNutting, C
dc.coverage.spatialNetherlands
dc.date.accessioned2021-11-23T14:14:35Z
dc.date.available2021-11-23T14:14:35Z
dc.date.issued2021-10-01
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/34754954
dc.identifierS2405-6316(21)00058-0
dc.identifier.citationPhys Imaging Radiat Oncol, 2021, 20 pp. 46 - 50
dc.identifier.urihttps://repository.icr.ac.uk/handle/internal/4895
dc.identifier.eissn2405-6316
dc.identifier.doi10.1016/j.phro.2021.10.003
dc.description.abstractThis study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial. Protocol compliant plans were used for a single benchmark planning case. Larger margins were associated with higher doses to adjacent organs at risk, particularly the inferior pharyngeal constrictor muscle, but coincided with some improved low dose target coverage. A 3 mm margin is recommended for this technique if local practices allow.
dc.format.extent46 - 50
dc.languageeng
dc.language.isoeng
dc.publisherELSEVIER
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectCERR, Computational Environment for Radiotherapy Research
dc.subjectDARS, dysphagia/aspiration related structures
dc.subjectDICOM, Digital Imaging and Communications in Medicine
dc.subjectDO-IMRT, dysphagia optimised intensity modulated radiotherapy
dc.subjectDysphagia
dc.subjectHead and neck cancer
dc.subjectICR-CTSU, Clinical Trials and Statistics Unit and the Institute of Cancer Research
dc.subjectIPCM, inferior pharyngeal constrictor muscle
dc.subjectIntensity modulated radiotherapy (IMRT)
dc.subjectNIHR, National Institute for Health Research
dc.subjectPAF, plan assessment form
dc.subjectQuality assurance
dc.subjectRTQA, radiotherapy quality assurance
dc.subjectRTTQA, UK’s National Radiotherapy Trials Quality Assurance Group
dc.subjectRandomised controlled trial
dc.subjectS-IMRT, standard intensity modulated radiotherapy
dc.subjectSMPCM, superior and middle pharyngeal constrictor muscles
dc.subjectTMG, Trial Management Group
dc.subjectVolumetric arc therapy (VMAT)
dc.titleQuality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer.
dc.typeJournal Article
dcterms.dateAccepted2021-10-10
rioxxterms.versionVoR
rioxxterms.versionofrecord10.1016/j.phro.2021.10.003
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0
rioxxterms.typeJournal Article/Review
dc.relation.isPartOfPhys Imaging Radiat Oncol
pubs.notesNot known
pubs.organisational-group/ICR
pubs.organisational-group/ICR/Primary Group
pubs.organisational-group/ICR/Primary Group/ICR Divisions
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies
pubs.organisational-group/ICR/Primary Group/ICR Divisions/Clinical Studies/Clinical Trials & Statistics Unit
pubs.publication-statusPublished online
pubs.volume20
pubs.embargo.termsNot known
icr.researchteamClinical Trials & Statistics Unit
dc.contributor.icrauthorHall, Emma


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