Quality assurance of dysphagia-optimised intensity modulated radiotherapy treatment planning for head and neck cancer.
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Date
2021-10-01ICR Author
Author
Tyler, J
Bernstein, D
Seithel, M
Rooney, K
Petkar, I
Miles, E
Clark, CH
Hall, E
Nutting, C
Type
Journal Article
Metadata
Show full item recordAbstract
This study aimed to assess the impact of the margin applied to the clinical target volume, to create the planning target volume, on plan quality of a novel dysphagia-optimised intensity modulated radiotherapy technique developed within a head and neck cancer multicentre randomised controlled trial. Protocol compliant plans were used for a single benchmark planning case. Larger margins were associated with higher doses to adjacent organs at risk, particularly the inferior pharyngeal constrictor muscle, but coincided with some improved low dose target coverage. A 3 mm margin is recommended for this technique if local practices allow.
Collections
Subject
CERR, Computational Environment for Radiotherapy Research
DARS, dysphagia/aspiration related structures
DICOM, Digital Imaging and Communications in Medicine
DO-IMRT, dysphagia optimised intensity modulated radiotherapy
Dysphagia
Head and neck cancer
ICR-CTSU, Clinical Trials and Statistics Unit and the Institute of Cancer Research
IPCM, inferior pharyngeal constrictor muscle
Intensity modulated radiotherapy (IMRT)
NIHR, National Institute for Health Research
PAF, plan assessment form
Quality assurance
RTQA, radiotherapy quality assurance
RTTQA, UK’s National Radiotherapy Trials Quality Assurance Group
Randomised controlled trial
S-IMRT, standard intensity modulated radiotherapy
SMPCM, superior and middle pharyngeal constrictor muscles
TMG, Trial Management Group
Volumetric arc therapy (VMAT)
Research team
Clinical Trials & Statistics Unit
Language
eng
Date accepted
2021-10-10
Citation
Phys Imaging Radiat Oncol, 2021, 20 pp. 46 - 50
Publisher
ELSEVIER
Except where otherwise noted, this item's license is described
as
https://creativecommons.org/licenses/by/4.0
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